The effect of Streptomyces coelicolor development on the hydrodynamics of a vertically orientated capillary membrane gradostat reactor

Godongwana, Buntu; Jager, Debbie De; Sheldon, Marshall Sheerene; Edwards, W

doi:10.1016/j.memsci.2009.01.051

Cited by 6 publications

(4 citation statements)

References 36 publications

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“…The rapid decline in the solute concentration in Figure 5(b) is due to increased radial convective flow in the dead-end mode. This results in nonuniform microbial growth/tapering as observed by Godongwana et al [18] for the bacterium Streptomyces coelicolor on a ceramic membrane. This phenomenon can be reduced by either increasing the solute flow rate or increasing the fraction retentate 𝑓.…”

Section: Comparison With Analytical Solutionmentioning

confidence: 82%

“…The solution domain is a regular 2-dimensional grid and is subdivided into 𝑚-intervals (of size ℎ) in the 𝑟-dimension and 𝑛-intervals (of size 𝑘) in the 𝑧-dimension. The difference equation (18), including the boundary conditions of (20), is solved by making use of the multivariate Newton-Rapshon iteration scheme:…”

Section: Finite-difference Schemementioning

confidence: 99%

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A Finite-Difference Solution of Solute Transport through a Membrane Bioreactor

Godongwana

Solomons

Sheldon

2015

Mathematical Problems in Engineering

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The current paper presents a theoretical analysis of the transport of solutes through a fixed-film membrane bioreactor (MBR), immobilised with an active biocatalyst. The dimensionless convection-diffusion equation with variable coefficients was solved analytically and numerically for concentration profiles of the solutes through the MBR. The analytical solution makes use of regular perturbation and accounts for radial convective flow as well as axial diffusion of the substrate species. The Michaelis-Menten (or Monod) rate equation was assumed for the sink term, and the perturbation was extended up to second-order. In the analytical solution only the first-order limit of the Michaelis-Menten equation was considered; hence the linearized equation was solved. In the numerical solution, however, this restriction was lifted. The solution of the nonlinear, elliptic, partial differential equation was based on an implicit finite-difference method (FDM). An upwind scheme was employed for numerical stability. The resulting algebraic equations were solved simultaneously using the multivariate Newton-Raphson iteration method. The solution allows for the evaluation of the effect on the concentration profiles of (i) the radial and axial convective velocity, (ii) the convective mass transfer rates, (iii) the reaction rates, (iv) the fraction retentate, and (v) the aspect ratio.

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Section: Comparison With Analytical Solutionmentioning

confidence: 82%

Section: Finite-difference Schemementioning

confidence: 99%

A Finite-Difference Solution of Solute Transport through a Membrane Bioreactor

Godongwana

Solomons

Sheldon

2015

Mathematical Problems in Engineering

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“…MBR systems can be distinguished according to the membrane process integrated [16,17]. Beyond pressure-driven methods (microfiltration, ultrafiltration, nanofiltration), other techniques like pervaporation, electrodialysis, and gas Anaerobic fluidized bed membrane bioreactor AFMBR [9] Anaerobic membrane bioreactor AnMBR [6][7][8][9][10][11] Airlift oxidation ditch membrane bioreactor AOXMBR [8] Bioelectrochemical membrane reactor BEMR [8] Batch granulation membrane bioreactor BG-MBR [8] Baffled membrane bioreactor BMBR [10] Electrochemical membrane bioreactor EMBR [8] Gas separation-membrane bioreactor GS-MBR [12] Hybrid-growth membrane bioreactor HG-MBR [9] Immersed hollow fiber membrane bioreactor IHFMB [13] Membrane electro-bioreactor MEBR [8] Membrane gradostat reactor MGR [14] Magnetically induced membrane vibration membrane bioreactor MMV-MBR [8] Membrane photobioreactor MPBR [8] Osmotic membrane bioreactor OMBR [7] Reciprocation membrane bioreactor rMBR [8] Single fiber membrane gradostat reactor SFMGR [14] separation can be applied. To connect these membrane processes to the bioreaction, careful design and optimization should be accomplished before starting the operation of MBRs.…”

Section: Novel Applications In Developing Stage 31 Types Of Mbrs Andmentioning

confidence: 99%

Integration of Membranes and Bioreactors

Bélafi–Bakó¹,

Bakonyi²

2019

Biotechnology and Bioengineering

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Combined application of bioreactors and membrane separations are considered as membrane bioreactors (MBRs). Examples for the application of MBRs are given in this chapter both for large scale (wastewater treatments) and in other areas in smaller scale. Wastewater treatments are the majority of the large-scale applications, where biological degradation is coupled with membrane filtration (microfiltration and ultrafiltration). Other types of MBRs include integration of biotransformations and bioconversions by microorganisms and enzymes with membrane separation processes, not only with filtration but also with pervaporation, electrodialysis, and gas separation. These MBRs provide significant advantages compared to the conventional batch bioprocesses. In this chapter, several examples are presented for both applications.

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“…One of the current research areas of interest into biofilm-attached membrane bioreactors (MBRs) is the development of cost-effective and environmentally friendly methods of producing various primary and secondary metabolites from bacterial, fungal, and yeast cells. These include: manganese and lignin peroxidase, secreted by the fungus Phanerochaete chrysosporium [1,2]; actinorhodin, a noncommercial antibiotic produced by the filamentous bacterium Streptomyces coelicolor [3]; glutamic acid, an ingredient in flavour enhancers of meats and vegetables, secreted by the bacterium Corynebacterium glutamicum [4]; ethanol, extracted from the yeast Saccharomyces cerevisiae [5]; and many others. With the exception of ethanol, these bioproducts are generally classified as products of intermediate value [6].…”

Section: Introductionmentioning

confidence: 99%

A Solution of the Convective-Diffusion Equation for Solute Mass Transfer inside a Capillary Membrane Bioreactor

Godongwana

Solomons

Sheldon

2010

International Journal of Chemical Engineering

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This paper presents an analytical model of substrate mass transfer through the lumen of a membrane bioreactor. The model is a solution of the convective-diffusion equation in two dimensions using a regular perturbation technique. The analysis accounts for radial-convective flow as well as axial diffusion of the substrate specie. The model is applicable to the different modes of operation of membrane bioreactor (MBR) systems (e.g., dead-end, open-shell, or closed-shell mode), as well as the vertical or horizontal orientation. The first-order limit of the Michaelis-Menten equation for substrate consumption was used to test the developed model against available analytical results. The results obtained from the application of this model, along with a biofilm growth kinetic model, will be useful in the derivation of an efficiency expression for enzyme production in an MBR.

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The effect of Streptomyces coelicolor development on the hydrodynamics of a vertically orientated capillary membrane gradostat reactor

Cited by 6 publications

References 36 publications

A Finite-Difference Solution of Solute Transport through a Membrane Bioreactor

A Finite-Difference Solution of Solute Transport through a Membrane Bioreactor

Integration of Membranes and Bioreactors

A Solution of the Convective-Diffusion Equation for Solute Mass Transfer inside a Capillary Membrane Bioreactor

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