The Effect of Stimulus Frequency on the Analgesic Response to Percutaneous Electrical Nerve Stimulation in Patients with Chronic Low Back Pain

Electroacupuncture analgesia with different frequencies is mediated via different opioid pathways in acute visceral hyperalgesia rats

“…These observations have subsequently been confirmed in controlled clinical studies on acute pain [4, 14,29] and chronic pain [12]. Hz).…”

The role of acupuncture in the management of subfertility

“…Both low-and high-frequency stimulations have been found to induce analgesia, but different types of endorphins are released depending on the stimulation pattern (27,28). Moreover, cumulative analgesic effects may be achieved by longer electric stimulation periods (29).…”

“…Most studies conducted on it suggest that body acupuncture may mediate effects through the activation of descending inhibitory pain control systems and the propriospinal heterosegmental antinociceptive system, which may lead to the slow regulation of pain-induced changes in signal transduction in the spinal cord (30)(31)(32)(33). Body acupuncture may also induce the release of various neurotransmitters such as b-endorphin, serotonin, encephalin, dynorphins, and substance P (28,29,34) in the central nervous system of both animals and humans. These may result in a similar regulation pathway of acupuncture.…”

Central Neuronal Plasticity, Low Back Pain and Spinal Manipulative Therapy

“…Finally, use of acupuncture, which is known to activate Ay-fiber and C-fiber afferents 74 and is suspected of triggering LTD, 41 has been shown to produce significant pain relief in patients suffering from low back pain. 75,76 In fact, a recent study 77 has demonstrated that the position of the acupuncture needle may not be critical in providing low back pain relief, thus suggesting that some central mechanism, eg, LTD, may be at work.…”