Background: Breast cancer is one of the most common cancers among women in the world. The study aims to analyze the effect of social capital, social support, hope, and self-compassion toward the quality of life of breast cancer survivors. Subjects and Method: It was a cross sectional study conducted from December 2019 -January 2020. The sample used was 200 breast cancer survivors aged ≥18 years old and were selected by using simple random sampling in Lovely Pink Community Solo. The dependent variable was the symptom and functional aspects of quality of life of breast cancer survivors. The independent variables were sociodemography factor, social capital, social support, hope, and self compassion. Data collection were conducted by using questionnaires. Data analysis was conducted by using path analysis with Stata 13. Results: Good quality of life among breast cancer survivors increased and was directly affected by symptom aspect with strong social support (b= 6.63; CI 95%= 2.52 up to 10.76; p= 0.002), high social capital (b= 3.73; CI 95%= 1.17 up to 6.30; p= 0.004), high self-compassion (b= 3.17; CI 95%= 0.57 up to 5.77; p= 0.017), education ≥high school (b= 4.19; CI 95%= 1.41 up to 6.97; p= 0.003), age ≥50 years (b= 1.78; CI 95%= 0.05 up to 3.51; p= 0.044), and high hope (b= 4.80; CI 95%= 1.85 up to 7.75; p= 0.001). Good quality of life among breast cancer survivors increased and was directly affected by functional aspects with strong social support (b= 3.13; CI 95%= 1.61 up to 4.64; p< 0.001), high social capital (b= 1.74; CI 95%= 0.31 up to 3.17; p= 0.017), high self-compassion (b= 1.60; CI 95%= 0.24 up to 2.94; p= 0.021), education ≥high school (b= 2.41; CI 95%= 0.95 up to 3.86; p= 0.001), age ≥50 years (b= 1.38; CI 95%= 0.11 up to 2.66; p= 0.034), and high hope (b= 2.42; CI 95%= 0.98 up to 3.86; p= 0.001). Conclusion: Good quality of life among breast cancer survivors in symptom and functional aspects is affected by strong social support, high social capital, high hope, high self-compassion, high education (≥high school), and age ≥50 years old.