The effect of silicone oil presence time on macular and choroidal thickness with macula-off rhegmatogenous retinal detachment

Karasu, Buğra; Eriş, Erdem; Sonmez, Orcun; Bekmez, Sinan

doi:10.1016/j.jfo.2019.10.017

Cited by 4 publications

(4 citation statements)

References 17 publications

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“…The final BCVA had no significant association with inner retinal change or SO tamponade duration in this study. This result is similar to that of a previous study [23,35]. Furthermore, Karasu et al reported that there was no statistically significant change in the macular thickness due to the SO tamponade period [35], and Rabina et al reported that the degree of retinal thinning did not correlate significantly with postoperative final visual acuity [23].…”

Section: Discussionsupporting

confidence: 89%

“…This result is similar to that of a previous study [23,35]. Furthermore, Karasu et al reported that there was no statistically significant change in the macular thickness due to the SO tamponade period [35], and Rabina et al reported that the degree of retinal thinning did not correlate significantly with postoperative final visual acuity [23]. However, Shalchi and Lee et al reported that inner macular thinning after SO tamponade can be related to poor visual outcomes [5,36].…”

Section: Discussionsupporting

confidence: 86%

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Retinal Changes before and after Silicone Oil Removal in Eyes with Rhegmatogenous Retinal Detachment Using Swept-Source Optical Coherence Tomography

Lee

Cho

Kang

et al. 2021

JCM

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This study aimed to evaluate and compare the retinal and choroidal thickness and vessel density (VD) changes between silicone oil (SO) tamponade and after SO removal using swept-source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). Thirty patients who underwent pars plana vitrectomy for retinal detachment (RD) with SO tamponade were included. SS-OCT and OCTA were conducted before RD surgery, during SO tamponade, and after SO removal. A 3-dimensional volumetric wide scan protocol was used for the analysis. The segmented retina, choroidal thickness map, and peripapillary thickness were then measured. For the OCTA analysis, 4.5 × 4.5 mm scans were used. Superficial and deep capillary plexus VDs in unaffected fellow eyes and eyes after SO removal were compared. During the SO tamponade period, the thickness of the parafoveal total retina, ganglion cell-inner plexiform layer, and peripapillary retinal nerve fiber layer (ppRNFL) were significantly thinner than those of unaffected fellow eyes (p < 0.05). The parafoveal layer thickness thinning recovered up to three to six months after SO removal. Moreover, six months after SO removal, the parafoveal thickness was not significantly different compared to that of unaffected fellow eyes (p > 0.05). However, the ppRNFL thickness was significantly decreased during SO tamponade and remained unrecovered six months after SO removal. There was no significant difference in the VD on the OCTA. Thus, SO tamponade and removal for RD resulted in a change in the retinal and peripapillary thickness. This may be due to the mechanical pressure effect of SO.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 86%

Retinal Changes before and after Silicone Oil Removal in Eyes with Rhegmatogenous Retinal Detachment Using Swept-Source Optical Coherence Tomography

Lee

Cho

Kang

et al. 2021

JCM

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“…In our study, there was no statistical difference between CT and fellow eyes before and after removal of SO, as the duration of SO tamponade did not last more than 6 months (102.19 ± 5.34 days). Previous studies have revealed CT differences between operated eyes and fellow eyes or before and after SO removal, which were considered statistically different after 6 months of SO tamponade [ 13 , 15 ]. This is consistent with the findings of our study.…”

Section: Discussionmentioning

confidence: 99%

Choroidal vascular changes in silicone oil-filled eyes after vitrectomy for rhegmatogenous retinal detachments

Chen,

Guan,

Liu

et al. 2023

BMC Ophthalmol

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Introduction The tamponade of silicone oil (SO) can affect both the structure and blood flow of the retina. However, there are few studies on the effect of SO tamponade on choroidal blood flow. Our study aimed to compare the effects of SO tamponade on the choroidal vascular index (CVI) and choroidal thickness (CT) in patients with unilateral rhegmatogenous retinal detachment (RRD) with operated eyes and fellow healthy eyes. Methods We retrospectively collected demographic and clinical data from 36 patients who underwent 23G pars plana vitrectomy and SO tamponade for unilateral complicated RRD. Enhanced depth imaging-optical coherence tomography (EDI-OCT) scans were performed both within 1 week before SO removal and at the last follow-up visit after SO removal. Using ImageJ software, images were binarized to segment the total choroidal area, luminal area, and stromal area, respectively. The CVI was calculated as CVI=(luminal area)/(total choroidal area), and CT was also evaluated. Results During SO tamponade, the CVI and luminal area in operated eyes were significantly lower compared to fellow eyes (57.616 ± 0.030 vs. 60.042 ± 0.019, P < 0.0001; 0.909 [0.694; 1.185] vs. 1.091 [0.785; 1.296], P = 0.007). Even after SO removal, the CVI remained lower in operated eyes than in fellow eyes (59.530 ± 0.018 vs. 60.319 ± 0.020, P = 0.031). Both CVI and luminal area were lower in operated eyes before SO removal than after SO removal (57.616 ± 0.030 vs. 59.530 ± 0.018, P = 0.0003; 0.909 [0.694; 1.185] vs. 0.994 [0.712; 1.348], P = 0.028). The duration of SO tamponade was positively correlated with the difference in CVI between fellow eyes and operated eyes during SO tamponade (P = 0.035). Total choroidal area, stromal area, and CT did not differ significantly between fellow eyes and operated eyes or between pre- and post-SO removal. Conclusions SO tamponade reduces CVI and decreases choroidal blood circulation in patients with retinal detachments required vitrectomy combined with SO tamponade. The longer the SO tamponade time, the more CVI reduction. In future work, we will aim to reduce these side effects by shortening the duration of silicone oil filling.

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“…This may affect the superficial capillary plexus (SCP) alone [ 156 , 159 ] or the deep capillary plexus (DCP) alone [ 160 , 161 ], whereas the involvement of both plexuses has been less commonly reported [ 160 ]. On the one hand, it has been hypothesized that the SCP and the superficial retinal layers, being in contact with SO, could be more susceptible to potential SO-related mechanical/cytotoxic damage [ 159 ]; on the other hand, the DCP is considered more susceptible to ischemic damage due to its intraretinal location [ 162 ]. In addition, Liu et al [ 163 ] speculated that the superficial vascular changes might also be related to the elevation of IOP as they found a decreased parafoveal SCP VD only in eyes that had experienced raised IOP during the follow-up.…”

Section: Retinal Changes Associated With Silicone Oilmentioning

confidence: 99%

Retinal and Corneal Changes Associated with Intraocular Silicone Oil Tamponade

Ferrara

Coco

Sorrentino

et al. 2022

JCM

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Silicone oils (SO) are used as long-term intraocular tamponades and have an irreplaceable role in vitreoretinal surgery. They can, however, be associated with multiple and potentially severe complications, involving different ocular tissues, in particular retina and cornea. Recent advances in ophthalmic imaging have allowed the precise characterization of retinal and corneal microstructural changes, at a subclinical level. This detailed analysis of SO-related retinal and corneal changes has improved our understanding of their pathogenesis and offer the potential for optimized monitoring and management of patients with SO-filled eyes. This review aims to provide clinicians and ophthalmic scientists with an updated and comprehensive overview of the corneal and retinal changes associated with SO tamponade.

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The effect of silicone oil presence time on macular and choroidal thickness with macula-off rhegmatogenous retinal detachment

Cited by 4 publications

References 17 publications

Retinal Changes before and after Silicone Oil Removal in Eyes with Rhegmatogenous Retinal Detachment Using Swept-Source Optical Coherence Tomography

Retinal Changes before and after Silicone Oil Removal in Eyes with Rhegmatogenous Retinal Detachment Using Swept-Source Optical Coherence Tomography

Choroidal vascular changes in silicone oil-filled eyes after vitrectomy for rhegmatogenous retinal detachments

Retinal and Corneal Changes Associated with Intraocular Silicone Oil Tamponade

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