The effect of silicone injections in the diabetic foot on peak plantar pressure and plantar tissue thickness: A 2-year follow-up

Schie, Carine H. van; Whalley, A; Armstrong, David G.; Vileikyte, Loretta; Boulton, Andrew J.M.

doi:10.1053/apmr.2002.33058

Cited by 47 publications

(29 citation statements)

References 23 publications

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“…Thus, the use of an "injectable orthosis" might well be beneficial in high-risk patients. Subsequent follow-up studies confirmed that the patients at greatest risk of ulceration (those with the highest baseline foot pressures) were most likely to benefit from silicone injections [68], but that after 2 years of follow-up, the benefits of injections, though still demonstrable, were reduced in comparison with baseline, suggesting that booster injection may be needed periodically [69]. This too is an area of current research.…”

Section: Foot Pressure Studies In Diabetesmentioning

confidence: 99%

The diabetic foot: from art to science. The 18th Camillo Golgi lecture

2004

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Diabetic foot ulceration represents a major medical, social and economic problem all over the world. While more than 5% of diabetic patients have a history of foot ulceration, the cumulative lifetime incidence may be as high as 15%. Ethnic differences exist in both ulcer and amputation incidences, with both being less common in patients of Indian subcontinent origin living in the UK. Foot ulceration results from the interaction of several contributory factors, the most important of which is neuropathy. With respect to the management of acute Charcot neuroarthropathy in diabetes, recent studies suggest that bisphosphonates reduce disease activity as judged not only by differences in skin temperature, but also by assessing markers of bone turnover. The use of the total-contact cast is demonstrated in the treatment of acute Charcot feet and of plantar neuropathic ulcers. Histological evidence suggests that pressure relief results in chronic foot ulcers changing their morphological appearance by displaying some features of an acute wound. Thus, repetitive stresses on the insensate foot appear to play a major role in maintaining ulcer chronicity. It is hoped that increasing research activity in foot disease will ultimately result in fewer ulcers and less amputation in diabetes.

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Section: Foot Pressure Studies In Diabetesmentioning

confidence: 99%

The diabetic foot: from art to science. The 18th Camillo Golgi lecture

2004

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“…29,30 Callus removal can reduce pressures by as much as 30%, although the durability of such relief is unknown. 31,32 Different interventions exhibit a great variation in off-loading capacity (Fig 2), and this likely influences their efficacy in preventing or healing foot ulcers in diabetic patients.…”

Section: The Evidence Base: What Work and What Does Not Work?mentioning

confidence: 99%

Off-loading the diabetic foot for ulcer prevention and healing

Cavanagh

Bus

2010

Journal of Vascular Surgery

145

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“…One RCT compared the pressure-reducing effect of regular liquid silicone injections and saline injections under callused metatarsal heads and found significantly reduced peak plantar pressures in the silicon group at 12 months, but not at 24 months follow-up [103]. In a subset analysis of a larger RCT [10], peak plantar pressures were evaluated in patients subjected to ATL + TCC treatment or to TCC alone [104].…”

Section: Surgical Offloadingmentioning

confidence: 99%

The effectiveness of footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in diabetes: a systematic review

Bus

Valk

Deursen

et al. 2008

Diabetes Metab. Res. Rev.

219

183

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SummaryBackground Footwear and offloading techniques are commonly used in clinical practice for the prevention and treatment of foot ulcers in diabetes, but the evidence base to support this use is not well known. The goal of this review was to systematically assess the literature and to determine the available evidence on the use of footwear and offloading interventions for ulcer prevention, ulcer treatment, and plantar pressure reduction in the diabetic foot.

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The effect of silicone injections in the diabetic foot on peak plantar pressure and plantar tissue thickness: A 2-year follow-up

Cited by 47 publications

References 23 publications

The diabetic foot: from art to science. The 18th Camillo Golgi lecture

The diabetic foot: from art to science. The 18th Camillo Golgi lecture

Off-loading the diabetic foot for ulcer prevention and healing

The effectiveness of footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in diabetes: a systematic review

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