The effect of serum levels of vitamin D in stone recurrencein patients with urinary tract stone

Mohammadalibeigi, Feramarz; Shirani, Majid; Motamedi, Mahsa

doi:10.15171/jrip.2018.19

Cited by 1 publication

(4 citation statements)

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“…Around 80-85% of RS are made up of calcium. 7 The commonest type of urolithiasis is Ca-oxalate, then mixed Ca-oxalate/phosphate, struvite, uric acid, Ca-phosphate, and cysteine RS. 2 However, blood alterations in Ca, Ph, PTH, and VitD3 metabolism have not been hitherto studied in patients with recurrent RS in Babylon.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, owing to it has renal and bone action, further elevates serum Ca-levels. 7 Furthermore, due to enhanced intestinal Ca-absorption, might reduce the intestinal binding of Ca to oxalate that in turn, encourages much oxalate absorption, thereby induce the exacerbation of hyperoxaluria. 15,16 The locations and sites of the stone in our work are consistent with other reports from Turkey and Iran, nonetheless the frequency of two-sided, presence of several RS and the size of RS were varied.…”

Section: Discussionmentioning

confidence: 99%

“…25,26 However, no significant relations had observed in a study conducted earlier among infants 14 and adults. 7,18 Though still debated, prior reports from tertiary referral centers verified VitD3 insufficiency induce hypocalcemia that, in-turn, increase PTH release or "secondary hyperparathyroidism'' . Higher levels of PTH in-turn elevate blood Ca.…”

Section: Originalmentioning

confidence: 99%

“…6 Nevertheless, the precise roles of these factors in urolithiasis remain to be clarified. 7 To assess the probable role of VitD3 and PTH as essential factors in the incidence of RS, we investigated their association with plasma calcium and phosphorus levels.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Calcium and Phosphate Homeostasis in Patients with Recurrent Nephrolithiasis

Masser,

Mousa,

Makki

et al. 2021

J. Contemp. Med. Sci.

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Objectives:The aim of the study was to evaluate the Calcium (Ca) and Phosphate (Ph) homeostasis and their association with plasma 25(OH)2 vitamin D3 (VitD3) and parathyroid hormone (PTH) in patients with recurrent nephrolithiasis. Methods: A cross-sectional, involved 100 confirmed patients with renal stone (RS). Their serum levels of Ca, PTH, Ph, and VitD3 had assessed. Biochemical analysis of renal calculi and crystals had been investigated also. The summary measures had described as mean+/-SD for continuous variables and frequencies/percentage for nominal variables. The mean serum Ca, Ph, PTH, and VitD3 were (8.01 ± 2.2 mg/dl, 2.9 ± 1.2 mg/dl, 56.7 ± 24.7 pg/dl, and 7.03 ± 4.2 pg/ml), respectively. Results: Almost all patients (97%) had a positive history of previous RS with a predominant family history in most instances (82%). There was a positive non-significant correlation between VitD3 with serum Ph and Ca. Whereas an inverse non-significant correlation between PTH with serum Ca and VitD3 had observed. Urinary crystals analysis revealed that uric acid represented 53% of the total crystals, followed by Ca-oxalate. Stone analyses revealed that around 3/4th of the cases had Ca-oxalate stone, followed by Ca-oxalate with uric acid, then Ca-phosphate, and the least type was mixed stone types. Conclusion:There was a positive non-significant correlation between VitD3 with serum Ph and Ca. There was an inverse non-significant correlation between PTH with serum Ca and VitD3. Serum Ca, and Ph were non-significant predictors of renal stones and/or urinary crystals.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%