The effect of seminal vesicle‐sparing radical prostatectomy on serum prostate‐specific antigen level

John, Hubert; Hauri, D.; Maake, Caroline

doi:10.1111/j.1464-410x.2003.04501.x

Cited by 19 publications

(7 citation statements)

References 15 publications

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“…The authors conclude that oncological follow-up in terms of postoperative PSA is not significantly different after SVRP compared with sRALP. This is in line with a previous study, performed in 2003, in which less sensitive PSA assays were used after SVRP [2].…”

supporting

confidence: 92%

Seminal vesicle sparing robotic radical prostatectomy – no different interpretation of postoperative PSA follow-up required?

2018

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Now in Swiss Medical Weekly, Burkhardt et al. present a retrospective study on the impact of seminal vesicle sparing robotic radical prostatectomy (SVRP) on postoperative prostate-specific antigen (PSA) levels measured with an ultrasensitive immunoassay [1]. The rationale of SVRP is to protect nerves that are responsible for erectile function and that are located close to the tips of the seminal vesicles. Because these remaining tips are known to produce PSA and PSA testing has become more sensitive during recent years, the authors aimed to reassess the influence of SVRP on postoperative PSA.

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confidence: 92%

Seminal vesicle sparing robotic radical prostatectomy – no different interpretation of postoperative PSA follow-up required?

2018

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“…Moreover, according to John et al [26] PSA from the seminal vesicles does not appear to be clinically signifi cant for serum PSA levels. Consequently, PSA relapse after seminal-sparing prostatectomy is not caused by the remaining seminal vesicle but rather indicates the presence of residual prostatic tissue or cancer micrometas tasis.…”

Section: Discussionmentioning

confidence: 99%

Seminal Monolateral Nerve-Sparing Radical Prostatectomy in Selected Patients

Bellina

Mari²,

Ambu³

et al. 2005

Urol Int

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Introduction: In recent years there has been a shift in prostate cancer stage with the majority of patients nowadays being operated with cT1c disease, prostate-specific antigen levels of <10 ng/ml, and a decreased rate of seminal vesicle invasion. Recent data suggest the role of preservation of the seminal vesicle in improving continence and/or potency. We describe our preliminary experience with seminal-sparing, unilateral nerve-sparing retropubic radical prostatectomy. Patients and Methods: 21 selected patients with clinically localized prostate cancer underwent seminal unilateral nerve-sparing retropubic radical prostatectomy (seminal-sparing group, SSG). We compared the postoperative continence, erectile function and quality of orgasm results to those obtained in a control group (CG) of 21 patients who underwent unilateral nerve-sparing radical prostatectomy. Sexual function was evaluated preoperatively and 9 months postoperatively with the 5-item International Index of Erectile Function (IIEF-5) questionnaire and with oth er self-administered questionnaires. The quality of orgasm was evaluated 9 months postoperatively. Results: 1 month postoperatively, 95 and 28% of the patients in the SSG and CG were continent (p < 0.001). The median postoperative drop in IIEF-5 score was 5 points in SSG and 14.5 points in CG (p < 0.0001). Nine months postoperatively, 90 and 62% of the patients in SSG and CG, respectively (p = 0.05), maintained the ability to achieve orgasm. Conclusions: In our experience seminal-sparing radical prostatectomy showed good feasibility and improved early postoperative urinary continence, erectile function and quality of orgasm, without compromised cancer control.

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“…Thus, any rise in serum PSA detected on follow up should still be attributed to residual prostatic tissue or metastasis. 30…”

Section: Surgical Technique Modificationsmentioning

confidence: 99%

“…Thus, any rise in serum PSA detected on follow up should still be attributed to residual prostatic tissue or metastasis. 30 This procedure is not currently accepted nor recommended for standard practice. With the recent use of magnetic resonance to predict the location and size of the prostate cancer prior to RP, there have been several experimental procedures tailored to treat only the index prostatic lesion.…”

Section: Seminal Vesicle Preservationmentioning

confidence: 99%

Anatomical, surgical and technical factors influencing continence after radical prostatectomy

Arroyo

Martini

Wang

et al. 2019

Therapeutic Advances in Urology

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Radical prostatectomy (RP) is the most frequent treatment with curative intent performed for prostate cancer to date. Different surgical approaches (perineal, transperitoneal, and extraperitoneal) and techniques (laparoscopic and robot assisted) have been described to increase the efficiency and potentially diminish the postoperative complications of this procedure.The aim of this narrative review is to investigate and define the factors that influence postprostatectomy urinary continence. We highlighted the anatomical landmarks and the modifications of surgical techniques aimed at improving the continence rates and thus, patient quality of life.After RP, the long-term continence rates range from 84% to 97%. In order to achieve good continence rates, a careful dissection along with meticulous anatomical reconstruction is required. To this end, a detailed knowledge of the periprostatic anatomy is mandatory.

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The effect of seminal vesicle‐sparing radical prostatectomy on serum prostate‐specific antigen level

Cited by 19 publications

References 15 publications

Seminal vesicle sparing robotic radical prostatectomy – no different interpretation of postoperative PSA follow-up required?

Seminal vesicle sparing robotic radical prostatectomy – no different interpretation of postoperative PSA follow-up required?

Seminal Monolateral Nerve-Sparing Radical Prostatectomy in Selected Patients

Anatomical, surgical and technical factors influencing continence after radical prostatectomy

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