The effect of selenous acid on the hematopoietic system of chicken embryos

Kury, George; Rev-Kury, Livia H.; Crosby, Roberta J.

doi:10.1016/0041-008x(67)90046-4

Cited by 9 publications

(2 citation statements)

References 8 publications

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“…However, these values are an order of magnitude higher than values for selenous acid (76.0-7600.0 µg/mL), which is associated with its toxic properties and characterizes the relatively lower toxicity of selenium nanoparticles. This is confirmed in the works [58,59], which present studies of the phytotoxicity, accumulation and transformation of various forms of selenium in garlic: selenite (Se +4 ), selenate (Se +6 ) and selenium nanoparticles. The authors showed that the phytotoxicity of SeNP is much lower than that of selenite and selenate.…”

Section: Effect Of Preparation Of Selenium Nanoparticles Stabilized With Pvp C15 (8 ± 2 Kda) and Ascorbic Acid On Morphofunctional Paramesupporting

confidence: 57%

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

et al. 2021

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Within the framework of this study, the effect of nanoparticles of the essential trace element selenium stabilized by Polyvinylpirrolidone (PVP) C15 (8 ± 2 kDa) and ascorbic acid on the germination of barley seeds has been studied. Selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid, characterized by a spherical shape, monodisperse size distribution, and a diameter of about 70 ± 5 nm, were obtained by the chemical reduction method. The experiment compared the effect of selenium nanoparticles and selenous acid on seed germination. The positive effect of preparation of selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid on the length of roots and shoots, the number of roots, and the percentage of seed germination has been revealed. It was determined that the highest percentage of Hordeum vulgare L. culture seed germination was achieved using a preparation of selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid at a concentration of of 4.65 µg/mL. Analysis of the results showed that selenium in the form of nanoparticles has an order of magnitude that is less toxic than in the form of selenous acid. The study of morphological and functional parameters during the germination of Hordeum vulgare L. seeds allowed us to conclude that selenium nanoparticles can be successfully used in agronomy and agriculture to provide plants with the essential microelement selenium, which is necessary for the normal growth and development of crops.

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Section: Effect Of Preparation Of Selenium Nanoparticles Stabilized With Pvp C15 (8 ± 2 Kda) and Ascorbic Acid On Morphofunctional Paramesupporting

confidence: 57%

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

et al. 2021

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“…The results of present study suggested that diets of 5∼15 mg/kg Se-induced G 0 /G 1 arrest, which could lead to cell cycle blockage, inhibit the proliferation of splenocytes and decrease the relative weight of spleen in vivo. The mechanisms of cell cycle arrest induced by excess Se are associated with following factors: (a) selenous acid caused a decrease in the uptake of thymidine in the lymphocytes of the spleen [18]. (b) DNA and RNA synthesis was inhibited by high concentration of Se [19,20].…”

Section: Proliferating Indexmentioning

confidence: 99%

Histological Lesion of Spleen and Inhibition of Splenocyte Proliferation in Broilers Fed on Diets Excess in Selenium

Peng

Cui

Deng

et al. 2010

Biol Trace Elem Res

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The purpose of this 42-day study was to investigate the effects of excess dietary selenium on immune function by determining morphological changes of spleen and cell cycle of splenocyte. Three hundred 1-day-old avian broilers were fed on a basic diet (0.2 mg/kg selenium) or the same diet amended to contain 1, 5, 10, and 15 mg/kg selenium (Se) supplied as sodium selenite (n = 60/group). Anatomically, the spleens were shrunken in volume with pallecent color. Histopathologically, lymphopenia in splenic nodules and periarterial lymphatic sheaths and congestion of the red pulp were observed in 5, 10, and 15 mg/kg Se group. By flow cytometry method, the percentage of G(0)/G(1) phase splenocytes was significantly increased, whereas the percentages of S phase and G(2)+M phase splenocytes and the proliferation index were markedly decreased in 5, 10, and 15 mg/kg Se groups when compared with those of 0.2 mg/kg group. The results confirmed that excess dietary Se as sodium selenite in the range of 5~15 mg/kg caused growth retardation of spleen by cell cycle blockage in young chickens.

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Chromosomal Analyses of Bone Marrow and Peripheral Blood in Subjects With a History of Illicit Drug Use

Amarose¹,

Schuster²

1971

Arch Gen Psychiatry

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The effect of selenous acid on the hematopoietic system of chicken embryos

Cited by 9 publications

References 8 publications

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

Histological Lesion of Spleen and Inhibition of Splenocyte Proliferation in Broilers Fed on Diets Excess in Selenium

Chromosomal Analyses of Bone Marrow and Peripheral Blood in Subjects With a History of Illicit Drug Use

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