The effect of resistin on the redox state of breast cancer cells
Elitsa Pavlova,
Radoslav Stojchevski,
Dimiter Avtanski
Abstract:Purpose
Resistin is an inflammatory cytokine secreted mostly by adipocytes and immune cells that plays a role in the development of insulin resistance, diabetes, and cancer. We hypothesized that resistin’s inflammatory activity influences the free radical and oxidative stress pathways.
Methods
We used human breast carcinogenic (MCF-7 and MDA-MB-231) and non-carcinogenic (MCF-10A) cells in this investigation and correlated the absorbed resistin conc… Show more
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