The effect of reparative regeneration of the liver on the mitotic activity of the corneal and epidermal epithelium in mice

Виноградова, Г. А.

doi:10.1007/bf00788842

Cited by 5 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present work shows that local factors alone are not sufficient to explain the changes observed. Increased mitotic activity in the corneal epithelium has been observed after liver trauma (Vinogradova 1961) and burning trauma of the opposite eye (Zhinkin et al 1951). The regeneration of corneal tissue therefore must be modulated by possibly systemic neuronal or humoral influence.…”

Section: Discussionmentioning

confidence: 99%

A previous abrasion in the contralateral eye influences the cell kinetics during healing of a central corneal abrasion

Estil¹,

Haaskjold²,

Bjerknes³

et al. 2001

Acta Ophthalmologica Scandinavica

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

A previous abrasion in the contralateral eye influences the cell kinetics during healing of a central corneal abrasion

Estil¹,

Haaskjold²,

Bjerknes³

et al. 2001

Acta Ophthalmologica Scandinavica

View full text Add to dashboard Cite

show abstract

“…In the rat and mouse, the corneal epithelium is a tissue having a marked rhythmic pattern of mitosis which has been demonstrated in several laboratories (1)(2)(3)(4)(5). A question naturally arises whether the synthesis of deoxyribonucleic acid (DNA) that occurs before observable mitosis also is rhythmic in rate over the same 24-hr period.…”

Section: Introductionmentioning

confidence: 99%

Circadian Phase Relationships of Thymidine-3h Uptake, Labeled Nuclei, Grain Counts, and Cell Division Rate in Rat Corneal Epithelium

Scheving

Pauly

1967

The Journal of Cell Biology

View full text Add to dashboard Cite

Significant differences in the uptake of thymidine-~H, percentage of labeled cells, numbers of grains per labeled nucleus, and mitotic rate were noted in rat corneal epithelium along a 24-hr time scale. These were demonstrated by injecting subgroups of five animals every hour during a 24-hr period with thymidine-3H, sacrificing thcm 2 hr later, and analyzing the corneal epithelium by scintillation counter and radioautographic techniques. The incrcasc in uptake during specific periods of the 24-hr time scale is attributed to an acceleration in the rate of DNA synthesis by individual cells and to an increase in the percentage of cclls in thc population activcly synthesizing DNA.

show abstract

“…MEYER (1954) reported a 24-hour rhythm in the corneal epithelium of frog larvae (one sample every two hours over a three-day period), VASAMA and V ASAMA (1957) found a diurnal rhythm in the corneal epithelium of mice with peak activity occurring at OS.OO and minimum at 22.00, and SCHEVING and CHIA-KULAS (1962) demonstrated a daily rhythm in the corneal epithelium of larval salamanders. Several Russian workers (GoLOLOBOBA, 1955;ALOV, 1959;KOSICHENKO, 1959 andVINOGRADOVA, 1961) also have reported diurnal changes in the cell division rate of this same tissue in both rats and mice.…”

Section: Discussionmentioning

confidence: 89%

The Cellular Aspects of Biorhythms

Mayersbach¹

1967

View full text Add to dashboard Cite

ForewordAlthough in the past the Swedish anatomical schools gave one of the first impulses to the study of biorhythms, this subject has never been a favourite matter of morphological investigations. The proposal of the organizing committee at the 8th International Anatomical Congress to organize a symposium on rhythmic research was willingly accepted. It was felt that as morphology is growing to be more and more an experimental discipline, biorhythms should be considered.It is gratefully acknowledged that investigators with great experience in biologic rhythms were prepared to take part in this symposium. Their different fields of research, physiology, biology, embryology and clinical, indicate the importance of rhythmic variations and mathematicians show how results gained have to be treated in a correct statistical fashion.There are the processes of cell multiplication, regeneration and growth, which have been proved to be rhythmic. The analyses of mitoses show to what extent such strong interventions as adrenalectomy, hypophysectomy etc. have been misinterpreted and delivered severally contradictory results when the rhythmic variations are not considered.The observation of tissues collected throughout 24 hours contributes to the much debated problem of "Amitosis" and also revealed a definite rhythm of DNA. In connection with this is the uptake and incorporation of DNA-precursors which occur rhythmically. In the vast number of precursor experiments which frequently vary strongly in their results, circadian changes have hardly been considered until now.It is not to be wondered at that biorhythmic oscillations are also expressed in the ultra-morphology, thus delivering pictures ranging from the "normal" of textbooks and atlases to those until now regarded as pathologic, or due to experimental influences, or technical mistakes.The group of histochemists finally communicate their results either by demonstrating the considerable size of variations in tissues and organs or by technical factors involved in the morphological analyses of rhythms. The latter brings new aspects in the histochemical technique and it seems that some hot discussions over enzyme localization, specifity, sex differences etc. resolves into a simple time factor, i. e. variations at the time of the day when tissues were removed for investigation.This symposium has given a wide view of the various aspects of biorhythms and it impresses the necessity for considering biorhythms in the interpretation of results in experimental morphology. The Springer Publishing Co., by publishing this Symposium, has made it possible to reach a much larger number of experimenters and we gratefully acknowledge our indebtedness to it.It is hoped that this symposium will serve as a guide, or at least as a sign post, in the fields of biological and medical research.

show abstract

The effect of reparative regeneration of the liver on the mitotic activity of the corneal and epidermal epithelium in mice

Cited by 5 publications

References 0 publications

A previous abrasion in the contralateral eye influences the cell kinetics during healing of a central corneal abrasion

A previous abrasion in the contralateral eye influences the cell kinetics during healing of a central corneal abrasion

Circadian Phase Relationships of Thymidine-3h Uptake, Labeled Nuclei, Grain Counts, and Cell Division Rate in Rat Corneal Epithelium

The Cellular Aspects of Biorhythms

Contact Info

Product

Resources

About