Abstract:In this experimental study propofol's hypotensive effect has been investigated. 30 rats were anesthetized and divided randomly into 3 groups. One group received propofol 10 mg/kg via the mesenteric vein while the other trasylol 100000 IU/kg intraperitoneally. The third group was for control. Serum PGE2 and histamine-like activities of the three groups were compared while carotid artery blood pressure was bein simultaneously recorded on the chimograph.
According to our results, histamine levels increased … Show more
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