2024
DOI: 10.20944/preprints202403.1456.v1
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The Effect of “Proanthocyanidin” on Ischemia-Reperfusion Injury in Skeletal Muscles of Rats

Abdullah Özer,
Başak Koçak,
Şaban Cem Sezen
et al.

Abstract: BACKGROUND: Lower limb skeletal muscle ischemia-reperfusion (IR) injury associated with increased morbidity and mortality is common in several clinical situations such as aortic aneurysms repairment, peripheral arterial surgery, vascular injury repairment, and shock. Although it is generally accepted that oxidative stress mediators have a significant role in IR injury, its precise mechanism is still unknown. Anecdotally, it is sustained not only by structural and functional changes in the organ it affects but … Show more

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