“…The symptom severity scores reduced from 53.2 ± 14.31 to 33.62 ± 16.94 after three months administration of evening primrose oil, while these amounts were 53.38 ± 13.93 and 50.27 ± 16.94 in placebo groups. A significant difference in PMS symptom severity scores was observed between placebo and evening primrose groups after three months of interventions ( P < 0.001) [12]. The results of the above clinical studies showed the efficacy and safety of evening primrose oil in the management of PMS during menstruation.…”
Section: Management With Evening Primrose Oilmentioning
Oenothera biennis
with the common name of “evening primrose” is containing a valuable fixed oil with commercial name of EPO. Evening primrose oil has two types of omega-6-fatty acid including linoleic acid (60%–80%) and γ-linoleic acid (8%–14%). Essential fatty acids are considered as essential compounds for body health, especially among women. The aim of this study was to evaluate the efficacy of evening primrose oil in the management of women ailments. The document was prepared by investigation in scientific articles of electronic resources (Google Scholar, PubMed, Science Direct, Wiley, Scopus, and Springer) by keywords of evening primrose oil and women. The results of our investigations showed that evening primrose oil has been the subject of several clinical studies, including premenstrual syndrome (PMS), hot flash, mastalgia, fibroadenomas, gestational diabetes, cervical ripening, and dilation. The major clinical studies are focused on mastalgia, followed by PMS. The results of studies confirmed the evening primrose oil's efficacy in women health, but the immediate response should not be expected from it, therefore, it should be regularly used up to 4 or 6 months.
“…The symptom severity scores reduced from 53.2 ± 14.31 to 33.62 ± 16.94 after three months administration of evening primrose oil, while these amounts were 53.38 ± 13.93 and 50.27 ± 16.94 in placebo groups. A significant difference in PMS symptom severity scores was observed between placebo and evening primrose groups after three months of interventions ( P < 0.001) [12]. The results of the above clinical studies showed the efficacy and safety of evening primrose oil in the management of PMS during menstruation.…”
Section: Management With Evening Primrose Oilmentioning
Oenothera biennis
with the common name of “evening primrose” is containing a valuable fixed oil with commercial name of EPO. Evening primrose oil has two types of omega-6-fatty acid including linoleic acid (60%–80%) and γ-linoleic acid (8%–14%). Essential fatty acids are considered as essential compounds for body health, especially among women. The aim of this study was to evaluate the efficacy of evening primrose oil in the management of women ailments. The document was prepared by investigation in scientific articles of electronic resources (Google Scholar, PubMed, Science Direct, Wiley, Scopus, and Springer) by keywords of evening primrose oil and women. The results of our investigations showed that evening primrose oil has been the subject of several clinical studies, including premenstrual syndrome (PMS), hot flash, mastalgia, fibroadenomas, gestational diabetes, cervical ripening, and dilation. The major clinical studies are focused on mastalgia, followed by PMS. The results of studies confirmed the evening primrose oil's efficacy in women health, but the immediate response should not be expected from it, therefore, it should be regularly used up to 4 or 6 months.
“…Hence, relieving PMS symptoms, especially mental symptoms, is reasonable. Vitamin B1 also stimulates the CNS and elevates mood, and subsequently, causes deep relaxation [43]. The active bioactive plant metabolite, a flavonoid present in chamomile, stimulates CNS.…”
Section: Mechanism Of Action Of Plan Productsmentioning
confidence: 99%
“…Abdollahifard et al (2014) [43],Ataollahi et al (2015) [48],Heidari et al (2019) [53], Farahmand et al (2020)[54], andFarahmand et al (2021) …”
Herbal medicine and nutritional supplements are suggested to treat premenstrual somatic and psycho-behavioural symptoms in clinical guidelines; nonetheless, this is at present based on poor-quality trial evidence. Hence, we aimed to design a systematic review and meta-analysis for their effectiveness in alleviating premenstrual symptoms. The published randomized controlled trials (RCTs) were extracted from Google scholar, PubMed, Scopus and PROSPERO databases. The risk of bias in randomized trials was assessed by Cochrane risk-of-bias tool. The main outcome parameters were analysed separately based on the Premenstrual Symptom Screening Tool and PMTS and DRSP scores. Secondary parameters of somatic, psychological, and behavioural subscale symptoms of PSST were also analysed. Data synthesis was performed assuming a random-effects model, and standardized mean difference (SMDs) was analysed using SPSS version 28.0.0 (IBM, Armonk, NY, USA). A total of 754 articles were screened, and 15 RCTs were included (n = 1211 patients). Primary results for participants randomized to an intervention reported reduced PSST (n = 9), PMTS (n = 2), and DSR (n = 4) scores with (SMD = −1.44; 95% CI: −1.72 to −1.17), (SMD = −1.69; 95% CI: −3.80 to 0.42) and (SMD = 2.86; 95% CI: 1.02 to 4.69) verses comparator with substantial heterogeneity. Physical (SMD = −1.61; 95% CI = −2.56 to −0.66), behavioural (SMD = −0.60; 95% CI = −1.55 to0.35) and mood (SMD = 0.57; 95% CI = −0.96 to 2.11) subscale symptom groupings of PSST displayed similar findings. Fifty-three studies (n = 8) were considered at low risk of bias with high quality. Mild adverse events were reported by four RCTs. Based on the existing evidence, herbal medicine and nutritional supplements may be effective and safe for PMS.
“…Moreover, the unsaturated fatty acids were known as vitamin F due to their significant role as bio-regulators and antioxidants (Babadzhanov et. al., 2004) and assumed to be responsible for many curative properties in the treatment of pre-menstrual tension, arthritis and as an auxiliary in weight loss (Saki, et al, 2015) as well as its role in treating atherosclerosis and hypercholesterolemia (Colla et al, 2008;Cingi et. al., 2008).…”
Section: Jelan Mofeed 90mentioning
confidence: 99%
“…As the fatty acids content considered to be affected by culture conditions, previous studies had carried out based on varying nutritional and physical conditions. Temperature (Colla et al, 2004), light (Oliveira et al, 1999;Ronda and Lele, 2008), pH, and even supplementation by additional nutrients (Ronda and Lele, 2008;Saki et al, 2015) were influencing parameters, enhancing Spirulina productivity, however it is better to combine more than one influencing parameter to obtain the maximum efficiency. Recently, permanently there is an interest to get a new combination of the influencing factors producing the maximum proportions of those important active compounds.…”
The valuable filamentous cyanobacterium, Arthrospira platensis or Spirulina platensis as it was commonly named for a long time; is a concentrated source of many active compounds, consumed by humans as a functional super-food used as a supplement/ingredient to enhance the human body performance or improve a specific function (Elshouny et al., 2017; Mostolizadeh et al., 2020). Spirulina platensis can produce beneficial compounds with therapeutic properties, characterized by fast digestion and absorption, so any of its nutritional benefits do not lose (Agustini and Wijayanto, 2020), which led some researchers to believe that Spirulina as an exceptional organism. Xuea et al., (2011) reported that the dry weight of Spirulina platensis contains protein by about 50-70 %, fiber 8-10 % and lipid 5-7 %. It also contains pigments (3-10 %), includes phycoerythrin and phycocyanin, which have potential properties as anti-aging, antimicrobials, anticancer,
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