The effect of preoperative biliary stenting on postoperative complications after pancreaticoduodenectomy

A Matched Case-Control Study of Preoperative Biliary Drainage in Patients with Pancreatic Adenocarcinoma: Routine Drainage Is Not Justified

“…[12][13][14][15][17][18][19] Despite these data, PBD continues to be a frequently performed procedure in patients being considered for resection of periampullary malignancy. In the current study, the majority of patients (59%) who underwent PD for pancreatic adenocarcinoma at our institution between 2000 and 2005 underwent PBD during their diagnostic evaluation.…”

“…12,13 Other centers have also shown a correlation between PBD and operative time and blood loss, positive bile cultures, wound infections, and pancreatic fistulae. [14][15][16][17][18][19] In addition to perioperative complications, PBD procedures can result in significant complications that can potentially delay operative intervention. 16 Despite these data, PBD continues to be routine.…”

Pancreaticoduodenectomy for periampullary malignancies: the effect of bile colonization on the postoperative outcome

“…However, the previously mentioned limitations and inconclusive results of the existing RCTs [15,16,[22][23][24][25] constitute evidence from retrospective studies of increased importance. Over the last 10 years, several retrospective studies examining the effect of PIBD on the postoperative outcome after pancreaticoduodenectomy for periampullary malignancies concluded that it did not increase major postoperative morbidity or mortality, excluding wound infections [4,[29][30][31][32][33][34], while others sited its adverse effect to the overall morbidity [35], pancreatic leak [36], or infectious complications [37] in univariate analyses.…”

Percutaneous transhepatic insertion of self-expanding short metal stents for biliary obstruction before resection of pancreatic or duodenal malignancy proves to be safe and effective

“…Evidence from animal studies suggests that internal biliary drainage to correct hyperbilirubinaemia leads to improved nutritional status, reduced risk of sepsis, and improved immune function [4,6,9]. In the clinical setting, several studies (mainly retrospective cohort studies) suggest that preoperative biliary drainage has little impact on postpancreatectomy morbidity, mortality, or survival [10][11][12][13][14][15]. In addition, some investigators have indicated that the incidence of infective complications among stented patients may be increased after surgery [16].…”