The effect of post-traumatic stress disorder on the risk of developing prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III

Hassan, Ahmed; Foll, Bernard Le; Imtiaz, Sameer; Rehm, Jürgen

doi:10.1016/j.drugalcdep.2017.07.012

Cited by 63 publications

(34 citation statements)

References 45 publications

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“…There is substantial research demonstrating that people with post‐traumatic stress disorder (PTSD) frequently have co‐occurring substance use disorders (SUD) and that they typically evidence greater impairment than individuals with either one or the other disorder . However, these investigations have taken different approaches when populating the groups, making comparisons across studies challenging.…”

Section: Introductionmentioning

confidence: 99%

“…We anticipated more individuals with life‐time PTSD/DUD would meet past‐year diagnostic criteria for one or more of the disorders comprising the comorbidity and would also evidence greater social and clinical impairment than those with life‐time PTSD/AUD . We also anticipated that the comorbid groups would evidence greater social and psychiatric impairment than their single disorder comparators .…”

Section: Introductionmentioning

confidence: 99%

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Clinical presentations, social functioning, and treatment receipt among individuals with comorbid life‐time PTSD and alcohol use disorders versus drug use disorders: findings from NESARC‐III

et al. 2019

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Aims To compare individuals with comorbid life-time post-traumatic stress disorder (PTSD) and alcohol use disorders [AUD; i.e. no drug use disorders (DUD)] with those with comorbid PTSD and DUD on past-year prevalence of these disorders, social functioning, life-time psychiatric comorbidities, and treatment receipt. The comorbid groups were also compared with their single diagnosis counterparts. Design and Setting Cross-sectional cohort study using data from the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC-III). Participants The total sample size was 36 309. Six groups were established: PTSD/AUD, PTSD/DUD, AUD, DUD, PTSD, and neither PTSD nor AUD/DUD. Life-time prevalence of AUD among those with PTSD/DUD was 80.2% and among those with DUD was 73.8%. Measurements The Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-5 version assessed lifetime and past-year psychiatric disorders and treatment receipt. Demographics and social stability indicators were queried. Group characteristics were summarized using weighted means. Prevalences and estimates for adjusted differences in means and adjusted odds ratios (aORs) were derived from multiple linear regression and logistic regression models, respectively. Analyses were conducted in R and accounted for the NESARC-III’s complex survey design, clustering, and non-response. Findings Compared with those with life-time PTSD/AUD, those with life-time PTSD/DUD were significantly less likely to have neither disorder in the past year (PTSD/AUD = 16.1%; PTSD/DUD = 8.5%; aOR = 0.54), and were more likely to report worse social and psychiatric functioning, and to have received both addiction and mental health treatment (PTSD/AUD = 18.4%; PTSD/DUD = 43.2%; aOR = 3.88). Compared with their single disorder counterparts, those with PTSD/DUD reported greater impairment than both groups, whereas the comorbid PTSD/AUD group differed more from the AUD than the PTSD group. Conclusions People with comorbid PTSD and drug use disorder have greater social and psychiatric impairment and may require different types and intensity of intervention than people with comorbid post-traumatic stress disorder and alcohol use disorder.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical presentations, social functioning, and treatment receipt among individuals with comorbid life‐time PTSD and alcohol use disorders versus drug use disorders: findings from NESARC‐III

et al. 2019

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“…Although these findings are limited to individuals who received a SAMFE, they provide an initial examination of prescription opioid misuse after a recent sexual assault. The data were collected prior to the wide dissemination of medication‐assisted treatments for prescription opioid use disorders within EDs nationwide; therefore, current use rates may differ . More research is needed to further understand the prospective correlates of prescription opioid misuse among samples of individuals who recently experienced a sexual assault.…”

Section: Resultsmentioning

confidence: 99%

“…These findings combined with the consistent cross‐sectional finding that sexual assault is associated with chronic pain among adults, it is essential to target prescription opioid misuse after sexual assault. Although there is limited research regarding prescription opioid misuse after recent sexual assault among adults, there is evidence that histories of traumatic event exposure are associated with higher rates of prescription opioid misuse among adults . To our knowledge, there are no studies examining the effect of interventions on prescription opioid misuse after a recent sexual assault.…”

mentioning

confidence: 99%

Prescription Opioid Misuse After a Recent Sexual Assault: A Randomized Clinical Trial of a Video Intervention

et al. 2019

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Background and Objectives Prescription opioid (PO) misuse is increasing and is associated with overdose. Individuals who experienced a recent sexual assault are at risk for increased substance use, yet limited interventions target PO misuse after sexual assault. The current study examined the efficacy of video interventions on PO misuse after sexual assault. Methods Adolescent girls and women (n = 154) were recruited in the context of a sexual assault medical forensic exam in the emergency department. Effects of a prevention of post‐rape stress (PPRS) video and a pleasant imagery and relaxation instruction (PIRI) video were compared with treatment as usual (TAU) during a sexual assault medical forensic exam on PO misuse. Participants reported if they had used POs for non‐medical purposes since the sexual assault at 1.5 month follow‐up. Results Results from a logistic regression analysis indicated that participants with a prior sexual assault were less likely to misuse prescription opioids 1.5 months after the assault in the PIRI condition compared with TAU. There were no main effects for video condition and no interactions for the PPRS condition on PO misuse. Discussion and Conclusions Providing the PIRI video, or teaching other types of mindfulness or relaxation exercises, may be warranted as a secondary prevention for individuals during the sexual assault medical forensic exam for those with a prior sexual assault history. Scientific Significance This research provides an initial examination of the impact of mindfulness skills recently after traumatic event exposure on PO misuse. (Am J Addict 2019;28:376–381)

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“…In the literature, different indications for substance choice in PTSD can be found. Some studies found common use of opioids in the PTSD group, suggesting that this situation might be related with the dysregulation of the opioid system in PTSD and an attempt at self-medication, while other studies did not find such a relation (56). Evidently, this area is in need of further study.…”

Section: Table 4: Comparison Of A-des Inventory Of Parents and Peer mentioning

confidence: 92%

Bir ÇEMATEM kliniğinde yatan ergen hastalarda madde kullanım eğilimleri, psikososyal travmalar, psikiyatrik komorbiditeler ve cinsiyet farklılıkları

Yıldız¹,

Ciftci²,

Yalcin³

2020

Dusunen Adam

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The effect of post-traumatic stress disorder on the risk of developing prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III

Cited by 63 publications

References 45 publications

Clinical presentations, social functioning, and treatment receipt among individuals with comorbid life‐time PTSD and alcohol use disorders versus drug use disorders: findings from NESARC‐III

Clinical presentations, social functioning, and treatment receipt among individuals with comorbid life‐time PTSD and alcohol use disorders versus drug use disorders: findings from NESARC‐III

Prescription Opioid Misuse After a Recent Sexual Assault: A Randomized Clinical Trial of a Video Intervention

Bir ÇEMATEM kliniğinde yatan ergen hastalarda madde kullanım eğilimleri, psikososyal travmalar, psikiyatrik komorbiditeler ve cinsiyet farklılıkları

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