The effect of positive end-expiratory pressure on pulse pressure variation

Smith, Francois Jacobus; Geyser, Marlize; Schreuder, Igne; Becker, P J

doi:10.1080/22201173.2012.10872874

Cited by 1 publication

(2 citation statements)

References 25 publications

(29 reference statements)

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“…Other thresholds are published in well circumscribed groups of patients (for a review see [ 28 ]). Smith and colleagues likewise described the effects of PEEP and called for a standardization of ventilatory settings when assessing volume responsiveness by PPV [ 29 ].…”

Section: Pulmonary Factorsmentioning

confidence: 99%

“…Cecconi and Rhodes, as a rare exception, drew attention to the fact that vascular tone may change during the volume challenge, invalidating the assessment of volume responsiveness [ 33 ]. Second, the fluid bolus must be standardized according to patient characteristics and vascular compliance (the suggestion of Smith and colleagues [ 29 ] to standardize ventilatory settings). Finally, and most importantly, PPV does not provide an assessment of optimum flow; it provides an estimate of whether flow can be increased by VE.…”

Section: Experimental Studies In Pulse Pressure Variationmentioning

confidence: 99%

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Pavane for a pulse pressure variation defunct

Søndergaard

2013

Crit Care

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Hemodynamic management of critically ill patients in the ICU or high-risk patients in the operating room has paradoxically shown progress in terms of outcome after the systematic application of volume responsiveness/flow optimization based on pulse pressure variation and/or stroke volume variation during controlled, positive-pressure ventilation in patients without spontaneous respiratory efforts. This assessment of circulatory optimization should ideally be based on an exhaustive, predictive and coherent physiological understanding of the cardiovascular system model. This paper sketches the extremely complex physiological background of the concept of volume responsiveness, concluding that it is not a reliable means of guiding hemodynamic optimization because it is based on a nonexhaustive, nonpredictive and incoherent physiological model.

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Section: Pulmonary Factorsmentioning

confidence: 99%

Section: Experimental Studies In Pulse Pressure Variationmentioning

confidence: 99%