The effect of polar groups on structural characteristics of phospholipid monolayers spread at the air–water interface

Miñones, J.; Patino, Juan M. Rodrı́guez; Conde, O.; Carrera, Cecilio; Seoane, R.

doi:10.1016/s0927-7757(01)01107-4

Cited by 106 publications

(98 citation statements)

References 40 publications

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“…For very large line tension, or very small domain size, the lowest energy shape is the one that minimizes the perimeter of the domain while keeping the area as a circle. 12 The morphology of the LC domains and the fluorescence phenomena were in accordance with the previous reports. 10,11 The formation of the defective LC domains in LB films induced by oxalate was attributed to the interaction between the negative-charged oxalate ions and the phosphoryl groups in DPPC headgroups.…”

Section: Methodssupporting

confidence: 91%

Induction of Ring‐Shaped Calcium Oxalate Patterns by Boundaries between Liquid Expanded Phase and Liquid Condensed Phase in Langmuir‐Blodgett Film

et al. 2008

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The formation of calcium oxalate kidney stones was related to injuries of renal epithelial membranes. The liquid condensed (LC) domains in Langmuir-Blodgett (LB) film of dipalmitoylphosphatidylcholine (DPPC) were used as a model system to induce crystal growth of urinary mineral calcium oxalate monohydrate (COM). The circular defective boundaries between the LC and liquid expanded (LE) phases of the DPPC monolayer could provide much more nucleating sites for crystallization of COM crystals. It induced ring-shaped or solid circular patterns of COM crystals on hydrophobic quartz substrates depending on the crystallization time.

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Section: Methodssupporting

confidence: 91%

Induction of Ring‐Shaped Calcium Oxalate Patterns by Boundaries between Liquid Expanded Phase and Liquid Condensed Phase in Langmuir‐Blodgett Film

et al. 2008

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“…As phospholipids [29] and other surfactants [30] containing a double hydrocarbon chain behaved in a similar way, we attribute this memory effect to an aggregation of the hydrophobic moieties of neighboring dU11 molecules at the air/water interface, despite the voluminous oligonucleotide head group. Rodríguez Patino et al reported for dipalmitoylphosphatidylcholine (DPPC) that the memory effect was more pronounced after the first isotherm than for the successive ones [31], similar to our observation.…”

Section: Film Stability At the Interfacementioning

confidence: 74%

Properties of amphiphilic oligonucleotide films at the air/water interface and after film transfer

Keller

Kwak

Vries

et al. 2013

Colloids and Surfaces B: Biointerfaces

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Properties of amphiphilic oligonucleotide films at the air/water interface and after film transfer Keller, R.; Kwak, M.; de Vries, J. W.; Sawaryn, C.; Wang, J.; Anaya, M.; Muellen, K.; Butt, H. -J.; Herrmann, A.; Berger, R. Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. b s t r a c tThe self-assembly of amphiphilic hybrid materials containing an oligonucleotide sequence at the air/water interface was investigated by means of pressure-molecular area (˘-A) isotherms. In addition, films were transferred onto solid substrates and imaged using scanning force microscopy. We used oligonucleotide molecules with lipid tails, which consisted of a single stranded oligonucleotide 11mer containing two hydrophobically modified 5-(dodec-1-ynyl)uracil nucleobases (dU11) at the 5 -end of the oligonucleotide sequence. The air/water interface was used as confinement for the self-assembling process of dU11. Scanning force microscopy of films transferred via Langmuir-Blodgett technique revealed mono-, bi-(˘ ≥ 2 mN/m) and multilayer formation (˘ ≥ 30 mN/m). The first layer was 1.6 ± 0.1 nm thick. It was oriented with the hydrophilic oligonucleotide moiety facing the hydrophilic substrate while the hydrophobic alkyl chains faced air. In the second layer the oligonucleotide moiety was found to face the air. The second layer was found to cover up to 95% of the sample area. Our measurements indicated that the rearrangement of the molecules into bi-and multiple bilayers happened already at the air/water interface. Similar results were obtained with a second type of oligonucleotide amphiphile, an oligonucleotide block copolymer, which was composed of an oligonucleotide 11mer covalently attached at the terminus to polypropyleneoxide (PPO).

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“…However, the chains can be tilted with respect to the membrane normal (Eeman and Deleu 2010). For the condensed state of monolayers, the tilt angle was estimated to be 29.6° ( Miñones et al 2002). In addition, the nature of the polar head group and the presence of counterions, which affect the head group conformation, may affect the tilt of the alkyl chains and, in turn, the interactions with liquid.…”

Section: Contact Angles Analysismentioning

confidence: 99%

Wettability of Binary Solid-Supported Films of Zwitterionic/Anionic Phospholipids

Jurak

2015

Adsorption Science & Technology

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ABSTRACT:The effect of different amounts of anionic phosphatidylglycerol in the zwitterionic phosphatidylcholine monolayers on their properties was quantitatively described in terms of the interactions between these two compounds as well as the changes of mixed monolayers' apparent surface free energy and its components. For all Langmuir films, surface pressure-area per molecule (π-A) isotherms were used to monitor the surface thermodynamics (i.e. the excess area and excess free enthalpy of mixing). This allowed to evaluate the kind and magnitude of interactions that have an influence on the phase behaviour and structural properties of the monolayers. Then, assuming that the molecular properties of Langmuir films are preserved upon transfer to a solid support, further characterizations were accomplished with advancing and receding contact angle measurements on the Langmuir-Blodgett films deposited at 35 mN/m on mica. These enabled the possibility to track changes in the wettability of the tightly packed or phase-separated phospholipid films and their surface free energy as a function of the monolayer composition. It is believed that these results throw a light on better understanding of the organizational structure of lipid films and their interactions with the surrounding environment. Moreover, the obtained results can be also helpful to identify the optimal lipid composition in the production of more effective therapeutic surfactants.

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The effect of polar groups on structural characteristics of phospholipid monolayers spread at the air–water interface

Cited by 106 publications

References 40 publications

Induction of Ring‐Shaped Calcium Oxalate Patterns by Boundaries between Liquid Expanded Phase and Liquid Condensed Phase in Langmuir‐Blodgett Film

Induction of Ring‐Shaped Calcium Oxalate Patterns by Boundaries between Liquid Expanded Phase and Liquid Condensed Phase in Langmuir‐Blodgett Film

Properties of amphiphilic oligonucleotide films at the air/water interface and after film transfer

Wettability of Binary Solid-Supported Films of Zwitterionic/Anionic Phospholipids

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