" The effect of Platelet Rich Plasma injection in treatment of Androgenetic alopecia patients "

Abstract

Background: Androgenetic alopecia (AGA) is an androgen-dependent, hereditary dermatological disorder , affecting men and women causing progressive thinning of the scalp hair in a defined Characteristic pattern, with significant negative impact on social and psychological state of patients. Aim of the work: To evaluate the efficacy and safety of Platelet Rich Plasma injection in androgenetic alopecia patients. Subjects and methods: A therapeutic trial study was carried out on a sample size of 20 patients with AGA who attended the outpatients' clinics of dermatology department -Zagazig University Hospitals. Results: At baseline, 16 patients (80%) had a positive pull test with a mean number of 9 hairs. At 4 th and 8 th week ,The hair loss decreased with a mean number of 5.5 and 3 hairs respectively . After PRP injection 2 patients (10%) achieved high improvement , 6 patients (30%) achieved moderate improvement , 6 patients (30%) achieved mild improvement and 6 patients (30%) achieved no change, with final patient's satisfaction (40%). Conclusion: PRP injection is relatively effective in treatment of Androgenetic alopecia.