The effect of plasma potassium on hospital length of stay in unselected acute admissions

Ellis, Harold; Sharpe, Claire C.; Kelly, P.; Al-Agil, Mohammad; Teo, James; Whyte, Martin

doi:10.1530/endoabs.77.p6

Cited by 1 publication

(2 citation statements)

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“…This meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was registered with PROSPERO (International Prospective Register of Systematic Reviews; registration identification CRD42021244454). 18 Comprehensive literature searches of the PubMed ( https://www.ncbi.nlm.nih.gov/pubmed/ ), and SCOPUS databases from were performed up to 19 March 2021 using the following combinations of keywords and medical subject heading terms without language restriction: ‘hyperkalaemia’ OR ‘hyperkal*’ OR ‘hypokalaemia’ OR ‘hypokal*’ OR ‘potassium’, AND ‘length of stay’, ‘emergency’, ‘cohort’, ‘admission’ and ‘outcome’. In addition, the reference sections of the included studies and review articles were reviewed to identify other relevant articles ( online supplemental appendix 1 ).…”

Section: Methodsmentioning

confidence: 99%

“…and was registered with PROSPERO (International Prospective Register of Systematic Reviews; registration identification CRD42021244454). 18 Comprehensive literature searches of the PubMed (https://www.ncbi.nlm. nih.gov/pubmed/), and SCOPUS databases from were performed up to 19 March 2021 using the following combinations of keywords and medical subject heading terms without language restriction: 'hyperkalaemia' OR 'hyperkal*' OR 'hypokalaemia' OR 'hypokal*' OR 'potassium', AND 'length of stay', 'emergency', 'cohort', 'admission' and 'outcome'.…”

Section: Open Accessmentioning

confidence: 99%

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Admission plasma potassium and length of hospital stay: a meta-analysis

Logan Ellis,

Llewellyn,

Mendis

et al. 2023

BMJ Open

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ObjectiveHypokalaemia and hyperkalaemia (‘dyskalaemia’) are commonly seen in patients requiring emergency hospital admission. The adverse effect of dyskalaemia on mortality is well described but there are few data for the effect on hospital length of stay. We sought to determine the association of serum potassium concentration with in-hospital length of stay.DesignSystematic review and meta-analysis.Data sourcesA structured search of MEDLINE, PubMed and SCOPUS databases to 19 March 2021.Eligibility criteriaObservational cohort studies defining exposure of interest as serum potassium levels (at admission or within the first 72 hours) and with outcome of interest as length of hospital stay. Studies had to provide estimates of length of stay as a comparison between normokalaemia and defined ranges of hyperkalaemia or hypokalaemia.Data extraction and synthesisWe identified 39 articles published to March 2021 that met the inclusion and exclusion criteria. Study selection, data extraction and quality assessment were carried out by two reviewers working independently and in duplicate, to assessed eligibility and risk of bias, and extract data from eligible studies. Random effects models were used to pool estimates across the included studies. Meta-analyses were performed using Cochrane-RevMan.ResultsFive studies were included in the meta-analysis. Compared with the reference group (3.5–5.0 mmol/L), the pooled raw differences of medians were 4.45 (95% CI 2.71 to 6.91), 1.99 (95% CI 0.03 to 3.94), 0.98 (95% CI 0.91 to 1.05), 1.51 (95% CI 1.03 to 2.0), 1 (95% CI 0.75 to 1.25) and 2.76 (95% CI 1.24 to 4.29) for patients with potassium levels of <2.5, 2.5 to <3.0, 3.0 to <3.5, <5 to 5.5, <5.5 to 6 and >6.0 mmol/L, respectively.ConclusionHospital length of stay follows a U-shaped distribution, with duration of admission being twofold greater at the extremes of the potassium range.

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Section: Methodsmentioning

confidence: 99%

Section: Open Accessmentioning

confidence: 99%