The effect of peritoneal lavage with a mixture of lincomycin–gentamicin on postoperative infection in cases of colorectal cancer surgery

ELsisy, Alaa A; Hagag, Mahmoud; Ewida, Marwan M

doi:10.4103/1110-2098.215454

Cited by 4 publications

(6 citation statements)

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“…IOPL with normal saline was found to be not associated with a significantly decreased risk of mortality, intra-abdominal abscess, incision surgical site infection, postoperative complications, reoperations, readmission, and number of positive cultures postoperatively compared to non-IOPL 1 , 7 , 8 .…”

Section: Indications For Different Agents In Peritoneal Lavagementioning

confidence: 79%

Intra-operative peritoneal lavage: normal saline, super-oxidized solution, antibiotics, or chemotherapy dilemma

Hezron,

Mashauri

2023

Annals of Medicine &Amp; Surgery

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Section: Indications For Different Agents In Peritoneal Lavagementioning

confidence: 79%

Intra-operative peritoneal lavage: normal saline, super-oxidized solution, antibiotics, or chemotherapy dilemma

Hezron,

Mashauri

2023

Annals of Medicine &Amp; Surgery

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“…A total of 9160 participants with CS were enrolled in the chosen studies; 4719 of them used TA, while 4441 served as controls. From a total of 2367 applicable studies that were appraised, 39 papers between 1967 and 2022 that met the inclusion criteria and were encompassed in the meta‐analysis were selected 12‐50 …”

Section: Resultsmentioning

confidence: 99%

“…From a total of 2367 applicable studies that were appraised, 39 papers between 1967 and 2022 that met the inclusion criteria and were encompassed in the meta‐analysis were selected. 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 …”

Section: Resultsmentioning

confidence: 99%

“…At the start of the investigations, 9160 participants with CS were enrolled in the chosen studies; 4719 of them used TA, while 4441 served as controls 12‐50 . Significantly lower SWIs post CS for TA as whole, GCA&D, TIFS, antibiotic powder, ointment, lavage, or injection for the abdominal wound (APOL), and ISD compared with control.…”

Section: Discussionmentioning

confidence: 99%

“…At the start of the investigations, 9160 participants with CS were enrolled in the chosen studies; 4719 of them used TA, while 4441 served as controls. 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 Significantly lower SWIs post CS for TA as whole, GCA&D, TIFS, antibiotic powder, ointment, lavage, or injection for the abdominal wound (APOL), and ISD compared with control. The low sample size (less than 100) of eight out of the 39 included studies in this meta‐analysis calls for precaution when analysing the outcomes.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A meta‐analysis examined the effect of topical nursing application of antimicrobial as a prophylaxis for the stoppage of surgical wound infection in colorectal surgery

Wang

Guo

et al. 2023

International Wound Journal

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To assess the impact of topical antimicrobial (TA) as a prophylaxis for the stoppage of surgical wound infection (SWI) in colorectal surgery (CS), we lead a meta‐analysis. 9160 participants with CS were enrolled in the chosen studies; 4719 of them used TA, while 4441 served as controls. To assess the effectiveness of TA application in lowering SWIs following CS, odds ratios (OR) with 95% confidence intervals (CIs) were computed with a dichotomous technique with a fixed‐ or random‐effect model. Significantly lower SWIs post CS for TA as whole (OR, 0.50; 95% CI, 0.38–0.64; P < .001), gentamicin collagen sponge and beads (OR, 0.52; 95% CI, 0.32–0.86; P = .01), triclosan impregnated fascial suture (OR, 0.57; 95% CI, 0.38–0.84; P = .005), antibiotic powder, ointment, lavage, or injection for the abdominal wound (OR, 0.35; 95% CI, 0.21–0.59; P < .001), and ionised silver dressing on the closed abdominal wound (OR, 0.45; 95% CI, 0.27–0.77; P = .003) compared to control. Significantly lower SWIs post CS for TA as a whole, gentamicin collagen sponge and beads, triclosan impregnated fascial sutures, antibiotic powder, ointment, lavage, or injection for the abdominal wound, and ionised silver dressing on the closed abdominal wound compared with control. The low sample size of 8 out of the 39 included studies in this meta‐analysis calls for precaution when analysing the outcomes.

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Effect of wound irrigation on the prevention of surgical site infections: A meta‐analysis

Fu¹,

Meng

Ma³

et al. 2022

International Wound Journal

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We performed a meta‐analysis to evaluate the effect of wound irrigation on the prevention of surgical site infections. A systematic literature search up to January 2022 was done and 24 studies included 4967 subjects under surgery at the start of the study; antibiotic irrigation was used with 1372 of them, 1261 were aqueous povidone‐iodine irrigation, and 2334 were saline irrigation or no irrigation for surgical site infections prevention in all surgical populations. We calculated the odds ratio (OR) with 95% confidence intervals (CIs) to evaluate the effect of different wound irrigation on the prevention of surgical site infections by the dichotomous method with a random or fixed‐influence model. Antibiotic irrigation had significantly lower surgical site infections in all surgical populations (OR, 0.48; 95% CI, 0.36‐0.62, P < .001) compared with saline irrigation or no irrigation for the subject under surgery. Aqueous povidone‐iodine irrigation had significantly lower surgical site infections in all surgical populations (OR, 0.40; 95% CI, 0.20‐0.81, P = .01) compared with saline irrigation or no irrigation for the subject under surgery. Antibiotic irrigation and aqueous povidone‐iodine irrigation significantly lowered surgical site infections in all surgical populations compared with saline irrigation or no irrigation for the subject under surgery. Further studies are required.

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The effect of peritoneal lavage with a mixture of lincomycin–gentamicin on postoperative infection in cases of colorectal cancer surgery

Cited by 4 publications

References 0 publications

Intra-operative peritoneal lavage: normal saline, super-oxidized solution, antibiotics, or chemotherapy dilemma

Intra-operative peritoneal lavage: normal saline, super-oxidized solution, antibiotics, or chemotherapy dilemma

A meta‐analysis examined the effect of topical nursing application of antimicrobial as a prophylaxis for the stoppage of surgical wound infection in colorectal surgery

Effect of wound irrigation on the prevention of surgical site infections: A meta‐analysis

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