“…In contrast to recent reports on evaluation of enhancement of ADR in sedated patients by new technologies 16,18,23,34,35 , focus on the withdrawal phase 10,21,22,25,26 and time of day 24 of colonoscopy or timing of bowel preparation 31 and removal of polyps during insertion 36 , we have described possible enhancement of proximal diminutive ADR on withdrawal in unsedated patients by the water method. Previous reports of worldwide availability of unsedated colonoscopy focused discussions on cecal intubation, patient tolerance, absence of sedation side-effects and potential cost savings 37 .…”