The effect of overactive bladder treatment with anticholinergics on female sexual function in women: a prospective observational study

Cakir, Suleyman Sami; Değirmentepe, Recep Burak; Atalay, Hasan Anıl; Canat, Lütfi; Özbir, Sait; Çulha, Mehmet Gökhan; Polat, Emre Can; Ötünçtemur, Alper

doi:10.1007/s11255-018-2030-7

Cited by 9 publications

(10 citation statements)

References 33 publications

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“…It has been favored by orthodontists in recent years, but it is unclear whether it is more conducive to the periodontal health of patients with periodontal disease [ 6 ]. Sami et al found that the current research on periodontal status during orthodontic treatment of periodontal disease is mostly about periodontal clinical indicators and plaque index, and there is relatively little about inflammatory factors [ 7 ]. Implant denture restoration is called the third set of human teeth because its biomechanical distribution is very close to natural teeth.…”

Section: Literature Reviewmentioning

confidence: 99%

Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis

Liu

2022

BioMed Research International

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In order to solve the effect of orthodontics combined with implant repair on the aesthetic effect and gingival crevicular fluid factor of patients with dentition defect and periodontitis, 60 patients who met the diagnostic criteria of chronic periodontitis were proposed. They were randomly divided into treatment group (taking Bushen Huoxue Guchi recipe for 3 courses while basic periodontal treatment) and control group (only basic periodontal treatment without taking any drugs). The experimental method of 30 cases in each group showed that PD, Al, and GI in the treatment group and control group decreased to varying degrees compared with those before treatment. The treatment group decreased significantly compared with the control group ( P < 0.01 ). Chronic periodontitis is a common clinical periodontal disease, accounting for up to 95%, local stimulation, a variety of anaerobic bacteria infection, and periodontal plaque, and other factors may cause the occurrence of diseases. Routine treatment mainly includes upper gingival cleaning, lower curettage treatment, and equal root surface treatment. Although the clinical symptoms can be alleviated to a certain extent, the cause cannot be fundamentally excluded, leading to the disease progression in some patients and the formation of aggressive periodontitis and necrotizing periodontal disease.

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Section: Literature Reviewmentioning

confidence: 99%

Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis

Liu

2022

BioMed Research International

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“…Compared to the baseline scores, all FSFI domains showed significant improvement after three months of beta-3 adrenergic agonist therapy. Also, Cakir et al investigated the effect of anticholinergics on sexual function in OAB patients 21 . They found that all FSFI domains except lubrication are improved with treatment though they showed no difference between different anticholinergic drugs.…”

Section: Discussionmentioning

confidence: 99%

The effect of solifenacin treatment for urge urinary incontinence on sexual function in premenopausal and postmenopausal women: a prospective observational study

EVRÜKE

TAŞ

2023

Cukurova Medical Journal

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Purpose: The aim of this study is to determine whether solifenacin used for urge urinary incontinence improves sexual function and if so this improvement differs between premenopausal and postmenopausal women. Materials and Methods: 120 women, 48 premenopausal and 72 postmenopausal were enrolled in the study. They filled out the Female Sexual Function Index (FSFI) before, three months, and six months after the solifenacin 5mg daily treatment for urge urinary incontinence. The results were interpreted in two groups, premenopausal and postmenopausal. The FSFI scores for baseline and for post-treatment were compared for both groups and with each other. Results: All domains of FSFI except orgasm were improved with the use of Solifenacin. The mean FSFI scores following three months (n=110) and six months (n=65) of solifenacin treatment are significantly improved compared to the baseline in both premenopausal and postmenopausal patients. This improvement in FSFI scores does not significantly differ between premenopausal and postmenopausal groups. Conclusion: Solifenacin treatment for lower urinary tract symptoms has been shown to have a positive impact on the sexual functions of both premenopausal and postmenopausal women. Although treatment with solifenacin improved sexual dysfunction in women, this improvement did not vary between premenopausal and postmenopausal women.

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“…By using FSFI evaluation, Zachariou et al 1 concluded that there was a significant increase in total FSFI scores in all domains in the group that received mirabegron. Cakir et al 25 prospectively enrolled 216 sexually active women with OAB and 165 healthy women (as the control group) in a study to test sexual function in women with OAB. Prior to treatment with anticholinergics and 3 months after treatment, women were asked to answer two questionnaires: the FSFI, an 8item OAB awareness tool, and the Beck Depression Inventory form.…”

Section: Pharmacotherapy Effect On Sexual Functionmentioning

confidence: 99%

“…The mean FSFI scores increased drastically in the group receiving anticholinergic treatment. 25 Del Rosso et al 26 treated 33 women diagnosed with OAB with 5 mg solifenacin (an antimuscarinic agent). They were re-evaluated after 3 months: 70% of the patients described improvement in sexual function (by using FSFI questionnaires).…”

Section: Pharmacotherapy Effect On Sexual Functionmentioning

confidence: 99%

Overactive Bladder Syndrome Treatments and Their Effect on Female Sexual Function: A Review

Levy

Löwenstein

2019

Sexual Medicine

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Introduction: Overactive bladder (OAB), the most common subtype of urinary incontinence, has a heavy price on quality of life, especially on sexual life. Unfortunately, most women rarely voice the worsening of sexual function, especially those who already suffer from OAB symptoms. It has been demonstrated that patients who suffer from OAB score lower on Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire and Female Sexual Function Index scores, meaning that their sexual function is debilitated. Therapies for OAB begin with traditional pelvic floor physiotherapy, advance to anticholinergic drugs, and become more invasive with intravesical injections of onabotulinumtoxinA (commonly known as Botox). Last, for patients resistant to conservative therapies, sacral neuromodulation is the treatment of choice. Methods: This article reviews the current literature that sheds light on the above 4 treatments and their effect on sexual function. This topic is of great importance because of the under-reporting of sexual dysfunction in women who suffer from OAB, in hopes of raising awareness of sexual function for clinicians treating patients with OAB. Results: This review found that the aforementioned 4 treatments for OAB (physiotherapy, anticholinergic drugs, intravesical injections of onabotulinumtoxinA, and sacral neuromodulation) do not have a detrimental affect on sexual function. On the contrary, the little data that do exist show that sexual function increases after these therapies are completed in women with OAB. Conclusion: This review concludes with a positive outlook: physicians are helping women with OAB syndrome to improve their sexual function. However, not enough data exist, partially due to under-reporting of diminished sexual function.

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The effect of overactive bladder treatment with anticholinergics on female sexual function in women: a prospective observational study

Cited by 9 publications

References 33 publications

Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis

Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis

The effect of solifenacin treatment for urge urinary incontinence on sexual function in premenopausal and postmenopausal women: a prospective observational study

Overactive Bladder Syndrome Treatments and Their Effect on Female Sexual Function: A Review

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