Abstract:The effect of the oral administration of oxyphenbutazone (Tandearil) on tumor growth and the levels of the seromucoid protein and seromucoid-bound carbohydrates of rats bearing Walker 256 has been studied. Oxyphenbutazone was administered at two dose levels, namely 60 mg/kg per day and 100 mg/kg per day. The anticipated elevation of seromucoid protein and seromucoid-bound carbohydrates was observed in untreated tumor-bearing rats. Oxyphenbutazone treatment suppressed the initial response of seromucoid protein … Show more
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