The effect of oral magnesium substitution on pregnancy-induced leg cramps

Seasonal effects on the occurrence of nocturnal leg cramps: a prospective cohort study

“…In regions above (British Columbia and the US) and below (Australia) the equator, the Internet search volume peaked in mid-summer and roughly doubled between the winter lows and summer highs. Although there are anecdotal reports of pregnancy-associated rest cramps being worse in summer, 5 these findings establish the phenomenon of seasonality in rest cramps in the general population.…”

“…3,4 It has been anecdotally reported that rest cramps in pregnant women are worse in summer. 5 Because the seasonality of rest cramps would come as a surprise to most clinicians, offer new therapeutic options and provide potential insight into the cause, we analyzed populationlevel data to determine whether the symptom burden of leg cramps varies seasonally in the general population.…”

Course of Maternal Serum Magnesium Levels in Low-Risk Gestations and in Preterm Labor and Delivery

“…Evaluating ionized magnesium levels is important to better understand magnesium metabolism in gestation [4,5,15]. Recent developments have largely overcome the technical problems of measuring ionized magnesium levels [5,16].…”

Restless legs syndrome and nocturnal leg cramps: review and guide to diagnosis and treatment

“…92 Other trials and a Cochrane review looking at the efficacy of magnesium citrate failed to show a significant benefit. [87][88][89][90] Most recently, in a randomized, double -blind, placebo -controlled clinical trial, Roguin Maor et al 91 demonstrated that oral magnesium oxide was not superior to placebo for older adults experiencing NLC.…”