The Effect of Obesity on Outcomes After Arteriovenous Fistulae Creation: A Systematic Review

Lee, Stefanie HT.; Ng, Jun Jie; Choong, Andrew M.T.L.

doi:10.1016/j.avsg.2023.02.005

Cited by 5 publications

(2 citation statements)

References 30 publications

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“…Obesity, along with high social and health costs, increases morbidity and mortality worldwide. As a result, several attempts are being made to find anti-obesity drugs worldwide [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Extraction, HPTLC Analysis and Antiobesity Activity of Jatropha tanjorensis and Fraxinus micrantha on High-Fat Diet Model in Rats

Srivastava

Virmani

Haque³

et al. 2023

Life

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The accumulation of body fat due to an imbalance between calorie intake and energy expenditure is called obesity. Metabolic syndrome increases the risk of heart disease, type 2 diabetes, and stroke. The purpose of this study was to determine the effect of Jatropha tanjorensis (J.T.) and Fraxinus micrantha (F.M.) leaf extracts on high-fat diet-induced obesity in rats. Normal control, high-fat diet (HFD) control, orlistat standard, and test groups were created using male Albino Wistar rats (n = 6 per group) weighing 190 ± 15 g. Except for the control group, all regimens were administered orally and continued for 6 weeks while on HFD. Evaluation criteria included body weight, food intake, blood glucose, lipid profile, oxidative stress, and liver histology. High-Performance Thin Layer Chromatography (HPTLC) analysis was performed using a solvent system (7:3 hexane: ethyl acetate for sitosterol solution and Jatropha tanjorensis extracts and 6:4 hexane: ethyl acetate: 1 drop of acetic acid for esculetin and Fraxinus micrantha extracts). There were no deaths during the 14 days before the acute toxicity test, indicating that aqueous and ethanolic extracts of both J.T. and F.M. did not produce acute toxicity at any dose (5, 50, 300, and 2000 mg/kg). The ethanolic and aqueous extracts of J.T. and F.M. leaves at 200 and 400 mg/kg/orally showed a reduction in weight gain, feed intake, and significant decreases in serum glucose and lipid profile. As compared to inducer HFD animals, co-treatment of aqueous and ethanolic extract of both J.T. and F.M. and orlistat increased the levels of antioxidant enzymes and decreased lipid peroxidation. The liver’s histological findings showed that the sample had some degree of protection. These results indicate that ethanolic samples of J.T. have antidiabetic potential in diabetic rats fed an HFD. The strong antioxidant potential and restoration of serum lipid levels may be related to this. Co-treatment of samples JTE, JTAQ, FME, FMAQ and orlistat resulted in an increase in antioxidant enzymes and reduction in lipid peroxidation as compared to inducer HFD animals. We report, for the first time, on using these leaves to combat obesity.

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Section: Introductionmentioning

confidence: 99%

Extraction, HPTLC Analysis and Antiobesity Activity of Jatropha tanjorensis and Fraxinus micrantha on High-Fat Diet Model in Rats

Srivastava

Virmani

Haque³

et al. 2023

Life

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“…This may be associated with the factor that the vascular access outcome is a result of the complex interplay of several risk factors, and patients on HD have heterogeneous characteristics. Vascular access outcomes are known to be influenced by various factors, including demographic factors such as age, sex, race/ethnicity; clinical comorbidities like cardiac, pulmonary, or peripheral vascular diseases, diabetes, obesity; as well as technical factors like surgical experience, vascular access care, intervention methods, needling practices, and post-needling care [19][20][21]. Vascular access-related outcomes of patients on HD are influenced not only by simple baseline characteristics and comorbidities but also by factors such as the vascular status, vascular access location or AVG presence, the specific HD center, and the experience of the nursing staff.…”

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confidence: 99%

Influence of renin–angiotensin system blockades on vascular access survival in patients on maintenance hemodialysis

Kang,

Kim,

Son

et al. 2023

Seminars in Dialysis

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IntroductionResults on the association between the use of renin–angiotensin system blockades (RASBs) and vascular access‐related outcomes are inconsistent. We aimed to compare vascular access‐related outcomes according to the use of RASBs in hemodialysis patients.MethodsThis study used data from a national hemodialysis quality assessment program of the Republic of Korea (n = 54,903). Group 1 was not prescribed any blood pressure‐lowering drugs (n = 28,521). Group 2 was prescribed other blood pressure‐lowering agents except for RASBs (n = 9571). Group 3 was prescribed RASBs (n = 16,811). Vascular access‐related outcomes were classified into intervention‐free survival (IFS), thrombosis‐free survival (TFS), and vascular access survival (VAS).ResultsNo significant difference in the three access survival rates was identified among the three groups. The multivariate Cox regression analyses indicated that Group 3 had better outcomes in IFS and TFS than Group 1. The numbers of angioplasties performed were significantly greater in Group 1 than in the other two groups. The numbers of thrombectomies performed were significantly the lowest in Group 3 among all the groups.ConclusionsOur study revealed different results according to types of access survival in univariate or multivariate analyses. The association of RASBs with favorable outcomes in vascular access remains unclear.

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Factors affecting suboptimal maturation of autogenous arteriovenous fistula in elderly patients with diabetes:A narrative review

Liu,

Wang,

et al. 2024

Heliyon

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The Effect of Obesity on Outcomes After Arteriovenous Fistulae Creation: A Systematic Review

Cited by 5 publications

References 30 publications

Extraction, HPTLC Analysis and Antiobesity Activity of Jatropha tanjorensis and Fraxinus micrantha on High-Fat Diet Model in Rats

Extraction, HPTLC Analysis and Antiobesity Activity of Jatropha tanjorensis and Fraxinus micrantha on High-Fat Diet Model in Rats

Influence of renin–angiotensin system blockades on vascular access survival in patients on maintenance hemodialysis

Factors affecting suboptimal maturation of autogenous arteriovenous fistula in elderly patients with diabetes:A narrative review

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