The effect of obesity on mid-term survival following coronary artery bypass surgery

Kuduvalli, Manoj; Grayson, Antony D.; Oo, Aung; Fabri, Brian M.; Rashid, Abbas

doi:10.1016/s1010-7940(02)00827-8

Cited by 52 publications

(55 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Like Kuduvalli et al we also could not find a significant difference for postoperative myocardial infarction [16]. This is in contrast with the study by Prasad et al where obese patients were more likely to have a myocardial infarction [10].…”

Section: Morbiditycontrasting

confidence: 82%

Influence of obesity on in-hospital and early mortality and morbidity after myocardial revascularization

Lindhout

Wouters

Noyez

2004

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

Objective: Obese patients are thought to have an increased risk for complications in coronary artery bypass surgery. Several risk stratification systems do not identify obesity as a variable for risk adjustment. The aim of this study is to evaluate the in-hospital and early (one year) mortality and morbidity in obese and non-obese patients after a CABG in the UMC St Radboud. Methods: The data of 1130 patients undergoing a myocardial revascularization from January 2000 to August 2002 were analyzed. Obesity was measured by the body mass index (BMI). A BMI $ 30 kg/m 2 was defined as obese. We compared 206 obese patients with 924 non-obese patients. Uni-and multivariate analysis were used to analyze the results. The 1-year survival was analyzed using Kaplan -Meier methods. Results: There were no significant differences between obese and non-obese patients according to postoperative myocardial infarction, re-operation for bleeding, in-hospital mortality, renal complications, neurological complications, pulmonary complications, gastrointestinal complications, re-intubation, re-admission on intensive care, ventilation time, days on intensive care, days in hospital and late mortality. Only the incidence of postoperative wound infections was increased in obese patients, 8.3% in the obese versus 4.4% in the non-obese ðP ¼ 0:02Þ: Multivariate analysis identified obesity only as risk factor for postoperative for wound infections (P ¼ 0:04; odds ratio: 1.97). Conclusions: Obese patients do not have an increased risk of in-hospital and early (1 year) mortality after CABG. However, obese patients have an increased risk of postoperative wound infections compared to non-obese patients. q

show abstract

Section: Morbiditycontrasting

confidence: 82%

Influence of obesity on in-hospital and early mortality and morbidity after myocardial revascularization

Lindhout

Wouters

Noyez

2004

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…3 In ENRICHD, prior to multivariable correction, a similar effect was observed. [5][6][7][8][9] After correction for confounders, the association disappeared.…”

Section: Discussionmentioning

confidence: 99%

“…Studies of patients undergoing revascularization have shown better outcomes or no increased risk in overweight and obese patients. [2][3][4][5][6] Many studies have shown either no association or a favorable effect of obesity in patients with MI; others only a modest association with recurrent events. 1,[7][8][9][10] A pooled analysis of CAD patients has shown an inverse J curve with patients with BMI between 30-35 having the lowest long-term mortality.…”

Section: Introductionmentioning

confidence: 99%

Weight Change after Myocardial Infarction—the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) Experience

López-Jiménez

Tian

et al. 2008

American Heart Journal

View full text Add to dashboard Cite

“…14) Other short-term adverse effects of blood transfusions in cardiac surgical patients have been documented well, but few studies have assessed long-term survival. 15,16) Despite all available evidence, transfusion practices vary substantially. 18,24) Deciding when a patient requires transfusion varies significantly among intensivists, anesthetists, and cardiac surgeons.…”

Section: Discussionmentioning

confidence: 99%

“…13) It also has been suggested that the BMI cutoff point for overweight or obesity in the Chinese population should be lower than WHO standards. 14) Therefore, we adopted the Chinese BMI cutoff values proposed by the Working Group on Obesity in China (WGOC) 15) and described in the Guidelines for Prevention and Control of Overweight and Obesity in Chinese Adults 16) to define overweight or obesity, as follows: BMI <18.5 kg/m 2 (underweight), 18.5≤ BMI <24 kg/m 2 (normal weight), 24≤ BMI <28 kg/m 2 (overweight), and BMI ≥28 kg/m 2 (obese). Because few patients were in the underweight group, we combined the underweight and normal weight groups (<24 kg/m 2 ).…”

Section: Study Populationmentioning

confidence: 99%

The Effects of Different BMI on Blood Loss and Transfusions in Chinese Patients Undergoing Coronary Artery Bypass Grafting

Wang

Chen

et al. 2017

ATCS

View full text Add to dashboard Cite

Objective: Blood loss is a predictor of outcomes after coronary artery bypass grafting (CABG). This study investigated the effects of body mass index (BMI) on blood loss, blood transfusion rate, and the variations in coagulation parameters of Chinese patients undergoing CABG. Methods: A total of 1007 Chinese patients who consecutively underwent isolated, primary CABG at Fuwai Hospital from January 1, 2013 to December 31, 2013 were included in this study. They were categorized by BMI into <24 kg/m 2 (low and normal weight group), 24≤ BMI <28 kg/m 2 (overweight group), and BMI ≥28 kg/m 2 (obese group). Following this BMI classification, the quantities of blood lost and recorded transfusions were analyzed. Results: Blood loss and transfusion rates were significantly higher in the low and normal weight group compared with the obese group (p <0.01). Chest tube drainage over 24 h, duration of intensive care unit (ICU) stay, and postoperative mechanical ventilation were higher as well (p <0.01). Atrial fibrillation was closely related to blood transfusion (p <0.001). Conclusions: Obesity is a predictor for protection against blood loss and transfusion in Chinese people. Patients with low and normal BMI lost more blood per kg of their weight and had higher total transfused volume during isolated primary CABG. Atrial fibrillation was associated with high blood transfusion.

show abstract

The effect of obesity on mid-term survival following coronary artery bypass surgery

Abstract: Although in-hospital mortality after CABG does not seem to be adversely affected by obesity there appears to be a significant increase in mortality in obese patients during a 4-year follow-up period.

Cited by 52 publications

References 16 publications

Influence of obesity on in-hospital and early mortality and morbidity after myocardial revascularization

Influence of obesity on in-hospital and early mortality and morbidity after myocardial revascularization

Weight Change after Myocardial Infarction—the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) Experience

The Effects of Different BMI on Blood Loss and Transfusions in Chinese Patients Undergoing Coronary Artery Bypass Grafting

Contact Info

Product

Resources

About