The Effect of Nutrition and Sleep Habits on Predisposition for Metabolic Syndrome in Greek Children

Katsa, Maria Efthymia; Ioannidis, Anastasios; Zyga, Sofia; Tsironi, Maria; Koutsovitis, Paraskevas; Chatzipanagiotou, Stylianos; Panagiotakos, Demosthenes B.; Sachlas, Athanasios; Kolovos, Petros; Routsi, Kleopatra; Pistikou, Anna Maria; Dimoliani, Dafni Eleni Kougioumtzi; Gil, Andrea Paola Rojas

doi:10.1016/j.pedn.2018.01.012

Cited by 12 publications

(31 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Metabolic syndrome (MetS) consists of 6 components that probably lead to type 2 diabetes mellitus and cardiovascular disease: central fat adiposity, hypertension, atherogenic dyslipidemia, glucose intolerance, a proinflammatory state, and a prothrombotic state [1]. These disturbances may occur in early childhood and persist into adulthood [2].…”

Section: Introductionmentioning

confidence: 99%

The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

Katsa

Ioannidis

Sachlas

et al. 2019

Ann Pediatr Endocrinol Metab

Self Cite

View full text Add to dashboard Cite

PurposeTo estimate the roles of triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio and uric acid in predisposition for metabolic syndrome (MetS) and its components in healthy children.MethodsAnthropometric and biochemical analyses were performed on 110 children, aged 5 to 12 years, from the Greek county of Laconia. The children were studied as a whole population and in separate groups according to age and predisposition to MetS after taking into consideration International Diabetes Federation criteria, body mass index, and lipid profile.ResultsSeventeen percent of children exhibited predisposition to MetS, while 39.1% had TG/HDL ratio >1, and 3.64% had high level of uric acid. According to a receiver operating characteristic curve analysis, the relative probability for MetS predisposition sextupled when TG/HDL ratio was ≥1 (odds ratio [OR], 5.986; 95% confidence interval [CI], 1.968–18.205). Children in the total population and those aged < 9 years had a greater probability for increased low-density lipoprotein (LDL) cholesterol (OR, 3.614; 95% CI, 1.561–8.365) when TG/HDL ratio was ≥ 1. The TG/HDL ratio was positively correlated with body mass index (BMI) (P=0.035) in children without MetS, cholesterol in the total population (P=0.06) and children ≥9 years old (P=0.026), and with LDL in the total population and both age groups (P=0.001). The TG/HDL ratio was also positively correlated with alanine aminotransferase in the total population (P=0.033) and gamma-glutamyl transferase in most studied groups (P<0.001). Uric acid was positively correlated with waist circumference in the total population (P=0.043) and in those without MetS (P=0.027). It was also positively correlated with BMI, TG, cholesterol, and TG/HDL ratio and negatively correlated with HDL in most studied groups (P<0.005).ConclusionsThe studied parameters correlated with MetS components and could be characterized as effective indexes for childhood MetS, regardless of age and predisposition to MetS.

show abstract

Section: Introductionmentioning

confidence: 99%

The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

Katsa

Ioannidis

Sachlas

et al. 2019

Ann Pediatr Endocrinol Metab

Self Cite

View full text Add to dashboard Cite

show abstract

“…The authors concluded that more weekend sleep could potentially mitigate the effect of sleep deprivation during weekdays on blood pressure (Gupta et al, ). Similarly, Katsa et al () reported the lifestyle habits in 480 children of 5‐12 years and showed that the hour of sleep before 22:00 h was strongly correlated with a decrease in waist circumference, and that short mid‐day naps were inversely associated with SBP and DBP. Additionally, the time of sleep was associated with DBP and fasting glucose, and fast food and meat consumption were associated with BMI and waist circumference.…”

Section: Discussionmentioning

confidence: 93%

“…Additionally, the time of sleep was associated with DBP and fasting glucose, and fast food and meat consumption were associated with BMI and waist circumference. Thus, diet and sleep habits apparently have an important role in the prevention of metabolic syndrome (Katsa et al, ). In a study of 2384 native Dutch, Ghanaian, Moroccan and African children of 5 years of age living in Amsterdam, and using a similar sleep time categorization (ie, low <10 h/night and normal sleep 10.0‐11.0 h/night), an increase in overweight was reported among Dutch and Moroccans participants with low sleep duration (Anujuo, Vrijkotte, Stronks, Jean‐Louis, & Agyemang, ).…”

Section: Discussionmentioning

confidence: 99%

Low sleep time is associated with higher levels of blood pressure and fat mass in Amerindian schoolchildren

Álvarez

Lucía

Ramírez‐Campillo

et al. 2019

American J Hum Biol

View full text Add to dashboard Cite

Objectives: While altered sleep patterns (ie, low sleep time) have been studied and reported in adults as a new cardiometabolic risk factor, less information is available on how sleep patterns impact children of different ethnicities. The aim of this study was to compare the levels of blood pressure and other cardiometabolic risk factors in relation to different levels of sleep time in schoolchildren of Amerindian Mapuche or European-ancestry of Southern Chile. Methods: In a cross-sectional study, 540 Chilean schoolchildren (6-13 years) were divided into two ethnic groups (n = 119 Mapuche Amerindians and n = 421 European-ancestry). Groups were analyzed according to sleep time per day as registered by parents' report and distributed into quartile categories of sleep time: Mapuche (quartile 1 [Q1] ≥10.0 h, n = 34; Q2 9.5-10.0 h, n = 29; Q3 8.5-9.0 h, n = 31; and Q4 ≤ 8.5 h, n = 25), and European (Q1, n = 99; Q2, n = 77; Q3, n = 144; Q4, n = 101). The main cardiovascular parameters (systolic [SBP] and diastolic blood pressure) were complemented with anthropometric/body composition (body mass, body mass index [BMI], waist circumference, fat mass, muscle mass, lean mass), cardiorespiratory (heart rate rest, oxygen saturation), and muscle strength (handgrip of dominant and non-dominant arm) outcomes. Results: From Q1 and across Q2, Q3, and Q4, there was an increase in delta mean SBP in both Mapuche (Δ +17.6 mm Hg) and European (Δ +7.3 mm Hg)schoolchildren with 30-90 min of decreased sleep time (using ≥10 h as reference in Q1). The tendency for worsening of other cardiometabolic risk factors was maintained for delta mean BMI (Δ +2.6 kg/m 2 ), waist circumference (Δ +12 cm), and fat mass (Δ +8.3%) in Mapuches, whereas European peers showed only worsened waist circumference (Δ +6 cm) across Q2, Q3, and Q4 in comparison with reference Q1. There was also a higher prevalence of hypertension in Mapuche (31.1%) compared to in European schoolchildren (17.6%).Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; HTN, hypertension; SBP, systolic blood pressure; WC, waist circumference.Conclusions: Mapuche and European schoolchildren show higher levels of SBP with a decrease in sleep time of 30 min; however, there is a higher prevalence of hypertension and obesity in ethnic Mapuches than in European schoolchildren.These findings indicate that more studies should be applied at early school ages for preventing low sleep time and their related cardiometabolic risk factors for hypertension development in different ethnic groups.

show abstract

“…αµύγδαλα), οι ιξώδεις ίνες (π.χ. ίνες από βρώµη και κριθάρι), οι πρωτεΐνες σόγιας και οι φυτικές στερόλες συµβάλλουν στη µείωση των λιπιδίων και στη µείωση του κινδύνου εκδήλωσης στεφανιαίας νόσου (Jenkins et al 2003, Katsa et al 2018. Είναι σηµαντικό να αναφερθεί ότι η υποκατάσταση των ζωικών πρωτεϊνών µε πρωτεΐνη σόγιας ή άλλες φυτικές πρωτεΐνες δύναται να µειώσει τη νεφρική υπερδιήθηση, την πρωτεϊνουρία και µακροπρόθεσµα να µειώσει τον κίνδυνο εµφάνισης νεφρικής νόσου στους ασθενείς µε Σ∆2 (Jenkins et al 2003).…”

Section: ∆ιατροφικές συνήθειεςunclassified

Alternative and complementary to medication therapies for type 2 Diabetes Mellitus

Katsa¹,

Adamopoulou²,

Gil

2019

HJNS

Self Cite

View full text Add to dashboard Cite

Type 2 Diabetes Mellitus is a global health issue which is associated with high risk for microvascular and macrovascular complications. Its treatment is based on the co-operation of an interdisciplinary healthcare team which helps the patient to combine the suitable medication with balanced lifestyle habits. In recent years, emphasis has been given to complementary to medication therapies. The purpose of this review is to present complementary to medication therapies for type 2 diabetes mellitus. In order to study this field a literature review in the databases such as Pubmed, Google Scholar was conducted during the period 2000-2018. Specifically, important is the role of micronutrients, such as: vitamin B3, vitamin E, magnesium for both prevention and treatment. According to traditional Chinese medicine, it is beneficial to consume specific plants and herbs, while the way in which they are prepared and consumed is important. Yoga also has a beneficial effect on patient's glycemic control and mental wellbeing. Acupuncture may be used as a supplemental therapy for type 2 diabetes mellitus, as it appears to enhance insulin synthesis. Massage is also helpful as it reduces heart rate and stress by the relaxation that causes. Hydrotherapy, chromotherapy and aromatherapy also appear to contribute to type 2 Diabetes Mellitus treatment by eliminating the toxins, triggering hormonal processes and reducing stress. It is remarkable that the use of alternative therapies is compatible with the use of conventional medicine. Their combination may provide an effective-holistic treatment for diabetic patients. This data should always be taken into consideration by healthcare professionals.

show abstract

The Effect of Nutrition and Sleep Habits on Predisposition for Metabolic Syndrome in Greek Children

Cited by 12 publications

References 37 publications

The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

Low sleep time is associated with higher levels of blood pressure and fat mass in Amerindian schoolchildren

Alternative and complementary to medication therapies for type 2 Diabetes Mellitus

Contact Info

Product

Resources

About