The effect of novel acridine-based agents with topoisomerase II inhibitor on mesothelioma cell proliferation and apoptosis.

Raza, Afsheen; Jacobson, Blake A.; Patel, M.; Benoit, Adam R.; Jay-Dixon, Joe; Ferguson, David M.; Kratzke, Robert A.

doi:10.1200/jco.2011.29.15_suppl.e13507

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2021

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“…A study by Raza et al (2011Raza et al ( , 2012 under in vivo conditions, but further modifications of these agents may help to produce more potent hTopoII catalytic inhibitors (Raza et al, 2011(Raza et al, , 2012.…”

Section: Introductionmentioning

confidence: 99%

Acridine derivatives as inhibitors/poisons of topoisomerase II

Kožurková

2021

J of Applied Toxicology

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The potential of acridines (amsacrine) as a topoisomerase II inhibitor or poison was first discovered in 1984, and since then, a considerable number of acridine derivatives have been tested as topoisomerase inhibitors/poisons, containing different substituents on the acridine chromophore. This review will discuss a series of studies published over the course of the last decade, which have investigated various novel acridine derivatives against topoisomerase II activity.

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Section: Introductionmentioning

confidence: 99%

Acridine derivatives as inhibitors/poisons of topoisomerase II

Kožurková

2021

J of Applied Toxicology

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The effect of novel acridine-based agents with topoisomerase II inhibitor on mesothelioma cell proliferation and apoptosis.

Cited by 1 publication

References 0 publications

Acridine derivatives as inhibitors/poisons of topoisomerase II

Acridine derivatives as inhibitors/poisons of topoisomerase II

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