Abstract:Non-rigid organ misregistration is an important problem for patients undergoing sequential quantitative SPECT for 3D dosimetry for targeted radionuclide therapy (TRT) treatment planning. This study aims to evaluate effects of these misregistrations on the accuracy of 3D dosimetry. We used 3 anatomical variations and 3 respective In-Ill Zevalin distributions of the digital 4D Extended Cardiac Torso (XCAT) phantom to model the deformation in different organs such as liver, kidneys, spleen and stomach. We simulat… Show more
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