The effect of noise exposure on the aging ear

Shone, G. R.; Altschuler, Richard A.; Miller, Josef M.; Nuttall, Alfred L.

doi:10.1016/0378-5955(91)90167-8

Cited by 65 publications

(25 citation statements)

References 18 publications

(1 reference statement)

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“…For example, the C57BL/6J strain exhibits AHL and has been used extensively to study presbycusis (Church and Shucard, 1986;Erway et al, 1996;Hunter and Willott, 1987;Johnson et al, 1997;McFadden and Willott, 1994;Parham, 1997;Shone et al, 1991;Walton et al, 1995;Willott et al, 1995). The C57BL/6J mice we tested for this study still had normal ABR thresholds at 33 weeks; however, by 100 weeks the same mice had ABR thresholds 60 dB above normal means (Table 3).…”

Section: Characteristics Of Hearing Loss In Impaired Strainsmentioning

confidence: 92%

Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

1999

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The common occurrence of hearing loss in both humans and mice, and the anatomical and functional similarities of their inner ears, attest to the potential of mice being used as models to study inherited hearing loss. A large-scale, auditory screening project is being undertaken at The Jackson Laboratory (TJL) to identify mice with inherited hearing disorders. To assess hearing sensitivity, at least five mice from each inbred strain had auditory brainstem response (ABR) thresholds determined. Thus far, we have screened 80 inbred strains of mice; 60 of them exhibited homogeneous ABR threshold values not significantly different from those of the control strain CBA/CaJ. This large database establishes a reliable reference for normal hearing mouse strains. The following 16 inbred strains exhibited significantly elevated ABR thresholds before the age of 3 months: 129/J, 129/ReJ, 129/ SvJ, A/J, ALR/LtJ, ALS/LtJ, BUB/BnJ, C57BLKS/J, C57BR/cdJ, C57L/J, DBA/2J, I/LnJ, MA/MyJ, NOD/LtJ, NOR/LtJ, and SKH2/J. These hearing impaired strains may serve as models for some forms of human non-syndromic hearing loss and aid in the identification of the underlying genes.

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Section: Characteristics Of Hearing Loss In Impaired Strainsmentioning

confidence: 92%

Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

1999

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“…Psychophysical experiments show that big brown bats do not suffer TTS, defined as threshold increases exceeding 6 dB, after extended exposure to intense ultrasonic broadband noise at a level and frequency range that could be encountered in the natural environment. In contrast, rodents, primates and humans all suffer TTS after comparable levels and durations of exposure to broadband noise within these species' hearing ranges (Ward et al, 1958;Mills et al, 1981;Nielsen, 1982;Shone et al, 1991). Previously, we suggested that terrestrial species may be more impacted by noise exposures because, unlike echolocating bats, they largely have evolved in quiet environments where natural occurrences of prolonged, intense sounds are rare .…”

Section: Introductionmentioning

confidence: 95%

“…In marked contrast, the passive hearing of terrestrial mammals can be severely impaired after exposure to broadband noise of even lower sound exposure levels (Ward et al, 1958;Mills et al, 1981;Shone et al, 1991;Nielsen, 1982). We hypothesize that the special demands of echolocation have contributed to the evolution of lessened susceptibility to noiseinduced hearing losses.…”

Section: Effects Of Noise On Echolocation Performancementioning

confidence: 99%

Echolocation behavior in big brown bats is not impaired after intense broadband noise exposures

Hom

Linnenschmidt

Simmons

2016

Journal of Experimental Biology

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Echolocating bats emit trains of intense ultrasonic biosonar pulses and listen to weaker echoes returning from objects in their environment. Identification and categorization of echoes are crucial for orientation and prey capture. Bats are social animals and often fly in groups in which they are exposed to their own emissions and to those from other bats, as well as to echoes from multiple surrounding objects. Sound pressure levels in these noisy conditions can exceed 110 dB, with no obvious deleterious effects on echolocation performance. Psychophysical experiments show that big brown bats (Eptesicus fuscus) do not experience temporary threshold shifts after exposure to intense broadband ultrasonic noise, but it is not known if they make fine-scale adjustments in their pulse emissions to compensate for any effects of the noise. We investigated whether big brown bats adapt the number, temporal patterning or relative amplitude of their emitted pulses while flying through an acoustically cluttered corridor after exposure to intense broadband noise (frequency range 10-100 kHz; sound exposure level 152 dB). Under these conditions, four bats made no significant changes in navigation errors or in pulse number, timing and amplitude 20 min, 24 h or 48 h after noise exposure. These data suggest that big brown bats remain able to perform difficult echolocation tasks after exposure to ecologically realistic levels of broadband noise.

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“…Rats exposed to highintensity tones (11-16 kHz, 120 dB SPL, 10 min; 156 dB SEL) experienced behavioral threshold increases between 10 and 60 dB, assessed 1 h post-exposure (Heffner et al, 2008). Shone et al (1991) reported ABR threshold increases in mice (CBA/Ca) of 30-35 dB (1 h post-exposure) in response to high-frequency tones after exposure to broadband noise (0.5-40 kHz, 101 dB SPL, 45 min; 135 dB SEL). These threshold increases are all higher than the maximum 5 dB increase shown by big brown bats in response to noise at a SEL of 152 dB.…”

Section: Tts In Other Mammalsmentioning

confidence: 99%

Broadband noise exposure does not affect hearing sensitivity in big brown bats (Eptesicus fuscus)

Simmons

Hom

Warnecke

2016

Journal of Experimental Biology

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In many vertebrates, exposure to intense sounds under certain stimulus conditions can induce temporary threshold shifts that reduce hearing sensitivity. Susceptibility to these hearing losses may reflect the relatively quiet environments in which most of these species have evolved. Echolocating big brown bats (Eptesicus fuscus) live in extremely intense acoustic environments in which they navigate and forage successfully, both alone and in company with other bats. We hypothesized that bats may have evolved a mechanism to minimize noise-induced hearing losses that otherwise could impair natural echolocation behaviors. The hearing sensitivity of seven big brown bats was measured in active echolocation and passive hearing tasks, before and after exposure to broadband noise spanning their audiometric range (10-100 kHz, 116 dB SPL re. 20 µPa rms, 1 h duration; sound exposure level 152 dB). Detection thresholds measured 20 min, 2 h or 24 h after exposure did not vary significantly from pre-exposure thresholds or from thresholds in control (sham exposure) conditions. These results suggest that big brown bats may be less susceptible to temporary threshold shifts than are other terrestrial mammals after exposure to similarly intense broadband sounds. These experiments provide fertile ground for future research on possible mechanisms employed by echolocating bats to minimize hearing losses while orienting effectively in noisy biological soundscapes.

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The effect of noise exposure on the aging ear

Cited by 65 publications

References 18 publications

Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

Echolocation behavior in big brown bats is not impaired after intense broadband noise exposures

Broadband noise exposure does not affect hearing sensitivity in big brown bats (Eptesicus fuscus)

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