The effect of natural polyphenol complex of red grape wine ON L-arginine/NO system

Sabadashka, Mariya

doi:10.15407/ubj86.01.117

Cited by 1 publication

(3 citation statements)

References 21 publications

(19 reference statements)

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“…The same effect was found in leukocytes, erythrocytes, pancreas and heart of rats with streptozotocin-induced diabetes mellitus [62]. It was detected a lowering in the total content of nitrites and nitrates in the case of X-ray irradiation in peripheral blood, leukocytes, aortic and renal tissues [40,45,[63][64][65][66]. Under conditions of streptozotocin-induced diabetes mellitus, it was observed a significant decrease in the content of nitrite and nitrate in leukocytes, in peritoneal macrophages and in pancreas in the case of polyphenol complex concentrate consumption.…”

Section: Antioxidant Potential Of Polyphenols Of Red Winesupporting

confidence: 67%

“…The following substances were detected in the obtained concentrate: anthocyanins (malvidin, delphinidin, peonidin, petunidin, cyanidin), flavones (quercetin, quercitin-3-O-glycoside), flavan-3-ols ((+)-catechins, (−)-epicatechins), phenolic acids (gallic, caftaric, coutaric, syringic). This spectrum of polyphenols probably determines the antioxidant and antidiabetic properties of the obtained concentrate [40,41].…”

Section: Composition Of Phenols In Grape Winementioning

confidence: 99%

“…Modern strategies aimed at limiting the formation of cytotoxins are the use of various herbal compounds with the ability to neutralize RNS in vitro, in particular, ONOO − , for example, phenolic compounds of grapes and grape wine [69]. It was shown that polyphenolic compounds from grape wine regulate the intensity of protein nitration processes in leukocytes, aorta and kidney cortical layer of irradiated rats and in erythrocytes of animals with diabetes mellitus [40,63,64]. The decrease in the content of 3′-nitrotyrosine-modified proteins may be due to the ability of grape polyphenolic compounds to detoxify NO, ONOO − , and other RNS.…”

Section: Antioxidant Potential Of Polyphenols Of Red Winementioning

confidence: 99%

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Red Wine and Yacon as a Source of Bioactive Compounds with Antidiabetic and Antioxidant Potential

Nagalievska¹,

Sabadashka²,

Sybirna³

2021

Alternative Medicine - Update

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Phytochemicals derived from different plants are promising therapeutic agents. Herbal compounds can be used under diseases, etiological causes of which are alterations of carbohydrate, protein, and lipid metabolisms, along with increased oxidative stress and chronic low-grade inflammation. Potential sources of biologically active substances may be grape wine, rich in phenolic compounds. Well-studied examples of polyphenols are phenolic acids, catechins, anthocyanins, and flavonoids, etc. Another source of biologically active compounds is yacon (Smallanthus sonchifolius Poepp. & Endl.). The aboveground part of yacon is rich in phenolic compounds and terpenes. Main biologically active substances from tuberous roots of yacon are fructooligosaccharides and phenolic compounds. The section will be devoted to the analysis of hypoglycemic and antioxidant effects, and molecular targets of the complex of biologically active substances derived from red wine and yacon.

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Section: Antioxidant Potential Of Polyphenols Of Red Winesupporting

confidence: 67%

Section: Composition Of Phenols In Grape Winementioning

confidence: 99%