The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies

Lange, Jan de; Baas, E.M.; Horsthuis, R.B.G.; Booij, A

doi:10.1016/j.ijom.2007.07.017

Cited by 14 publications

(4 citation statements)

References 11 publications

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“…The addition of adrenaline to nasal cocaine preparations has been shown to increase vasoconstriction and reduce blood loss with no adverse effect, by reducing the systemic absorption of cocaine . Nevertheless, four of the six case reports reviewed highlight adverse effects of this combination as a topical preparation in nasal surgery.…”

Section: Discussionmentioning

confidence: 99%

Assessing the safety and efficacy of drugs used in preparing the nose for diagnostic and therapeutic procedures: a systematic review

Saif

Farboud

Delfosse

et al. 2016

Clinical Otolaryngology

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For operative procedures, such as septorhinoplasty, a single agent tetracaine or levobupivicaine provides an improved surgical field. In functional endoscopic sinus surgery, lidocaine-adrenaline preparations have resulted in significantly better surgical and patient outcomes. There is little evidence to support the routine use of pre-procedural nasal preparation for flexible nasendoscopy. Those undergoing rigid endoscopy conversely always require the use of a vasoconstrictor and local anaesthetic. Pre-procedure assessment of patients is recommended, with agents being reserved for those with low pain thresholds, high anxiety and small nasal apertures presenting resistance to the insertion of the endoscope.

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Section: Discussionmentioning

confidence: 99%

Assessing the safety and efficacy of drugs used in preparing the nose for diagnostic and therapeutic procedures: a systematic review

Saif

Farboud

Delfosse

et al. 2016

Clinical Otolaryngology

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show abstract

“…The explanatory variables did not include data on vasoconstrictors. However, previous studies have reported the effects of adding adrenaline to local anesthetics 10,21) and of cocaine and adrenaline on nasal mucosa bleeding during a LFI 22) . Differences in surgeons and surgical techniques may have had an impact on the findings.…”

Section: ⅳ．Discussionmentioning

confidence: 95%

Factors Affecting Intraoperative Blood Loss in Orthognathic Surgery : A Monocentric Retrospective Study

Sayaka,

Hirotoshi,

Shigeru

2024

J. Stomatol.Soc.,Jpn.

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Ⅰ．IntroductionOrthognathic surgery(OGS)is widely recognized as a form of orthodontic treatment and was previously performed chiefly on the mandible, but in the quest for better outcomes, an increasing number of orthognathic surgeries are now being performed on the upper or lower jaw 1) . With improvements in surgical technique, ready availability of autologous blood, and the introduction of hypotensive anesthesia, surgery can be performed without recourse to allogeneic blood transfusions 1) . To date, a nationwide survey 1,2) by the Japanese Society for Jaw Deformity Research and clinical statistics 3 5) from various institutions have been published, but there are few studies of differences in blood loss due to anesthetic management methods. Therefore, the present, retrospective, observational study examined anesthesia management method as an explanatory variable, analyzed intraoperative blood loss as an outcome, and examined factors independently affecting the amount of intraoperative blood loss. This study was approved by the Ethics Review Board of the study center(No. 5 12)and adheres to the tenets of the Helsinki Declaration and STROBE guideline. Ⅱ．Objects and Methods Intotal, 157 patients who underwent a Le Fort I osteotomy (LFI) plus sagittal splitting ramus osteotomy (SSRO)or SSRO alone between April 2010 and March 2023 at Tokyo Metropolitan Tama Medical Center were included. Intraoperative blood loss in the anesthesia records of patients was used as the objective variable. The explanatory variables, including basic patient information(age, sex, height, weight, and BMI) , anes-

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“…In that respect, we found that in 22 out of 51 papers, the method of measuring estimated blood loss was missing . In 18 out of 51 papers, the estimated blood loss was measured by deducting the volume of saline used from the total volume in the suction unit and by weighing the sponges [31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48], others 10 mL [43]. In 6 out of 51 papers, losses in sponges were not included Table 1.…”

Section: Measurement Of Blood Lossmentioning

confidence: 99%

Bloodloss and Transfusion Need in Orthognathic Surgery: Review of Literature

Politis¹,

Agbaje²,

Lambrichts³

2018

EDUJ

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Background: Blood loss during orthognathic surgery has gained renewed interest due to the omission of surgical final splints in bimaxillary surgery, which increased operative time, while orthognathic surgery is increasingly indicated for the treatment of the obstructive sleep apnea syndrome (OSAS). OSAS subjects are usually older with more medical comorbidity which requires blood transfusion. Objective: To review (reported) blood loss and transfusion practice in orthognathic surgery in the literature published between 1976 and 2012 and to compare these data with more recent developments. The relationship between the duration of the surgery and the related blood loss and/or transfusion was examined. Data Sources: The 1976-2012 orthognathic literature was searched to determine the relationship between the duration of the surgery and the related blood loss and/or transfusion. Study Selection: Articles containing clear information on the operation time, blood loss, transfusion, and orthognathic surgery were included. Data Extraction: Information on the operation time, blood loss, transfusion, and orthognathic surgery was extracted. Data Synthesis: Different descriptions of procedures and techniques are grouped together in a concise and coherent way, resulting in a number of categories per label. Using this grouping various targeted questions are exploited and answered.

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The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies

Cited by 14 publications

References 11 publications

Assessing the safety and efficacy of drugs used in preparing the nose for diagnostic and therapeutic procedures: a systematic review

Assessing the safety and efficacy of drugs used in preparing the nose for diagnostic and therapeutic procedures: a systematic review

Factors Affecting Intraoperative Blood Loss in Orthognathic Surgery : A Monocentric Retrospective Study

Bloodloss and Transfusion Need in Orthognathic Surgery: Review of Literature

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