Background: Today, improving the quality of life for the elderly is of great importance. In addition, creating a favorable environment for the elderly has become a common concern worldwide. Objectives: The aim of this study was to assess the psychometric properties of the Persian version of quality of life (CASP-19) in older people. Methods: The study included 200 participants. The CASP-19 quality of life instrument for older people was adapted to Persian language through a translation and translation-back procedure. Afterwards, the reliability (internal consistency and test-retest) and validity (including face validity, content validity, factor analysis, known groups, and criterion validity), through assessing the correlation between the Persian version of the CASP-19 and the SF-36, were measured.