“…To induce stress, the included studies employed ionizing radiations (n=9) (21, 39, 46, 48-50, 59, 60, 64) and chemical agents (n=34) (14, 19, 20, 22, 31-38, 40-45, 47, 51-58, 61-63, 65-68). For chemical therapy, methotrexate (58,62), paclitaxel (63), busulfan (19, 32-34, 45, 53-55, 65, 67, 68), cisplatin (14,20,22,37,(40)(41)(42)(43)(44)47), doxorubicin (51,57,66), vinblastine (22), bleomycin (20,22), cyclophosphamide (31,47,52,61), etoposide (20), Taxol (35), procarbazine (36), docetaxel (38), and chlorambucil (56) were employed. Melatonin was administered intraperitoneal (IP, n=32) (14, 19-22, 31-41, 43, 45-47, 49, 50, 53-55, 58-61, 63-68) and oral (n=8) (42, 44,48,51,52,56,57,62).…”