The effect of melasma on self-esteem: A pilot study

Jiang, Jingzhi; Akinseye, O.; Tovar‐Garza, Andrea; Pandya, Amit G.

doi:10.1016/j.ijwd.2017.11.003

Cited by 64 publications

(68 citation statements)

References 12 publications

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“…O uso de ácido tranexâmico no tratamento de melasma moderado a grave vem sendo recentemente indicado por sua eficácia terapêutica alcançada com poucos efeitos colaterais (Jiang et al, 2018 Sendo assim, os estudos atestam a eficácia do uso de ácido tranexâmico no tratamento do melasma, principalmente pela segurança do seu uso, sem efeitos colaterais significativos, entretanto, afirmam a necessidade da realização de novas pesquisas para determinar os mecanismos do ácido tranexâmico nesse tratamento, definir a sua frequência de uso, benefícios e malefícios a longo prazo e uso de terapias combinadas (Ebrahimi & Naeini, 2014;Atefi et al, 2017;Xu et al, 2017).…”

Section: Tratamentos Utilizando áCido Tranexâmicounclassified

Manejo do melasma em mulheres adultas

Barbosa¹,

Costa²,

Borges³

et al. 2021

RSD

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Objetivo: Descrever os tratamentos disponíveis para melasma em mulheres adultas. Metodologia: Trata-se de uma revisão integrativa acerca dos tratamentos disponíveis para mulheres adultas com melasma, por meio de buscas nas seguintes bases de dados: Medical Literature Analysis and Retrieval System (MEDLINE/PubMed), Scientific Electronic Library Online (SciELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Ao todo foram incluídos 23 artigos na presente revisão. Resultados: Após análise dos tratamentos empregados nos trabalhos selecionados, identificou-se cinco categorias de tratamentos, sendo eles: utilização de ácido tranexâmico, tratamentos com microagulhamento, tratamentos com laser, tratamentos com extratos vegetais e outros tratamentos. Conclusão: Este artigo considerou que ao comparar o tratamento tópico com ácido tranexâmico e hidroquinona os resultados são semelhantes, no entanto a segunda opção apresenta mais efeitos adversos. Em pacientes que apresentam recidivas frequentes a associação do microagulhamento contribui com aumento da eficácia do ácido tranexâmico, sendo a terapia com laser outra opção de manejo nesses casos. Ademais, as formulações contendo extratos vegetais apresentam melhora das manchas hipercrômicas, assim como outros tratamentos.

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Section: Tratamentos Utilizando áCido Tranexâmicounclassified

Manejo do melasma em mulheres adultas

Barbosa¹,

Costa²,

Borges³

et al. 2021

RSD

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“…The exact cause is unknown but risk factors for melasma are well‐established and include a history of sun exposure as well as exposure to visible light, Fitzpatrick skin types greater than III, pregnancy, the use of exogenous hormones such as the oral contraceptive pill and hormone replacement therapy, as well as a family history . There is also emerging evidence for a significant vascular component in melasma lesions; affected skin has an increased density of dermal blood vessels compared to normal perilesional skin.…”

Section: Introductionmentioning

confidence: 99%

“…Although melasma is asymptomatic, it is a disfiguring skin disease that has a negative impact on quality of life and the self‐esteem of affected individuals . Though the majority of cases affect females, males still account for <20% of cases …”

Section: Introductionmentioning

confidence: 99%

Melasma: A critical analysis of clinical trials investigating treatment modalities published in the past 10 years

Spierings

2019

J of Cosmetic Dermatology

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Background: Melasma is an acquired disorder of facial pigmentation which is a treatment challenge.Aims: The aim of this article is to critically appraise the clinical trial evidence for different treatment modalities for melasma, published in peer-reviewed journals in the past 10 years. Patients/Methods: The literature review was conducted using PubMed and MEDLINE. The search was performed in July 2019, and search parameters were limited to all English language articles published in the past 10 years only.Results: Eighty-nine clinical trials were found. Four clinical trials investigated topical hydroquinone, supporting its safety and efficacy as first-line treatment. Twelve studies showed tranexamic acid as very promising. Nineteen studies assessed various novel oral, injectable, and topical treatments and highlight some new potential future treatments. Forty-two studies investigated laser and light treatment in melasma:LFQS laser is still one of the best options, especially in darker skin types. However, the picosecond laser has shown excellent results. Finally, 11 studies looked at peels.Overall, peels have not been shown to be superior to the use of topical therapy alone. Conclusion:Topical therapy with a HQ and retinoid-based product should be first line for a minimum of 3 months with the addition of oral tranexamic acid at 250 mg BD if no contraindication. Second-line treatment with lasers includes the LFQS Nd:YAG, picosecond laser, and the pulsed dye laser in lighter skin types. Third-line therapy would be the addition of chemical peels to the above treatments, with GA or TCA peels having the most evidence for effectiveness. K E Y W O R D Shydroquinone, melasma, pigmentation, tranexamic acid, tretinoin | INTRODUC TI ONMelasma is a common, acquired disorder of facial pigmentation which poses one of the greatest treatment challenges to the dermatologist and the aesthetic practitioner. Clinically, it is characterized by irregular brown macules and patches on the face. 1The exact cause is unknown but risk factors for melasma are wellestablished and include a history of sun exposure as well as exposure to visible light, Fitzpatrick skin types greater than III, pregnancy, the use of exogenous hormones such as the oral contraceptive pill and hormone replacement therapy, as well as a family history. 2 There is also emerging evidence for a significant vascular component in

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“…Pigmentary disorders have a well-demonstrated impact on patient quality of life, and as a result, they are a common cause for seeking dermatologic care. [1][2][3] Melasma is a chronic, acquired pigmentary disorder that presents with hypermelanosis of sunexposed areas of skin. Female predominance has been demonstrated in various studies, and this disorder, also known as the "mask of pregnancy," often plagues gravid women.…”

Section: Introductionmentioning

confidence: 99%

Treatment of melasma: a review of less commonly used antioxidants

Babbush

Khachemoune

2020

Int J Dermatology

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Melasma, a common cause for seeking dermatologic care, is a chronic condition of skin hyperpigmentation. With a poorly understood pathogenesis, and no universal cure, melasma is a challenge for many dermatologists. For decades, there has been investigation into the role of oxidative stress in melasma. In this literature review, we introduce the role of oxidative stress in melasma and discuss the function of various topical and oral antioxidant therapies for patients suffering from melasma. Numerous studies have shown efficacy of various antioxidant therapies for treatment of hyperpigmentation, and in this review, we focus primarily on those with less widespread use. Vitamin E, niacinamide, polypodium leucotomos, pycnogenol, grape seed extract, amino fruit acids, phytic acid, zinc, silymarin, Korean red ginseng powder, plant extracts, and parsley all have well‐demonstrated evidence of antioxidant properties, and these substances have been studied in the context of skin hyperpigmentation. Although there is conflicting evidence of their therapeutic efficacy, the use of these naturally occurring substances is promising for patients and medical providers seeking alternative therapeutic options.

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The effect of melasma on self-esteem: A pilot study

Cited by 64 publications

References 12 publications

Manejo do melasma em mulheres adultas

Manejo do melasma em mulheres adultas

Melasma: A critical analysis of clinical trials investigating treatment modalities published in the past 10 years

Treatment of melasma: a review of less commonly used antioxidants

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