The Effect of Maternal Hypoxia on the Heart Rate of the Foetus in Utero

John, Alison E.

doi:10.1093/bja/37.7.515

Cited by 7 publications

(3 citation statements)

References 9 publications

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“…An increase in maternal oxygen tension, both in the ewe and the mare, increased oxygen levels of the foetus (Comiine and Silver, 1970), although this effect is limited by placental oxygen consumption, by maternal oxygen carriage (the mother's blood is already nearly saturated at normal inspired tension), and by uneven distribu-tion of placental flow (Dawes, 1963). Similar results have been found in women in labour both when the maternal arterial oxygen was increased Gare et al, 1969) or decreased , the latter consistently causing changes in the foetal heart rate (John, 1965). This relationship has been confirmed when the mother is having inhalation drugs as general anaesthetics (Davey et al, 1967;Rorke, Davey and DuToit, 1968;Baraka, 1970).…”

Section: Is Additional Oxygen Of Value During Inhalationsupporting

confidence: 61%

Recent Advances in Pain Relief in Childbirth I: Inhalation and Systemic Analgesia

Rosen

1971

British Journal of Anaesthesia

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Section: Is Additional Oxygen Of Value During Inhalationsupporting

confidence: 61%

Recent Advances in Pain Relief in Childbirth I: Inhalation and Systemic Analgesia

Rosen

1971

British Journal of Anaesthesia

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“…83 " 85 The mild tachycardia observed in some of these studies may have been induced by maternal anxiety or catecholamine release. When mothers breathed 10% oxygen, fetuses exhibited severe acidosis and late cardiac decelerations.…”

Section: Fetal Habituation and Compromisementioning

confidence: 93%

Fetal Habituation

Hepper

Leader

1996

Fet. Matern. Med. Rev.

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One aim of obstetric practice is to ensure the wellbeing of the fetus. This is by no means an easy task and recent years have seen the development of a variety of tests, with varying degrees of success, to evaluate fetal health.Fetal wellbeing may be assessed at a variety of levels: genetic/cellular, physical/structural or functional. Ideally the evaluation of fetal health should provide information about the functional outcome of any particular condition, especially the performance of the central nervous system. Current tests may not do this. Thus, whilst tests of the fetal chromosomal or genetic constitution may determine the presence of particular genetic/chromosomal conditions, they may not predict functional outcome especially the functioning of the cerebral cortices, the ultimate arbiter of excellence in man. For example, Down's syndrome may be accurately diagnosed by analysis of fetal cells to detect the presence of Trisomy 21 but this in itself provides little information on the subsequent functional performance of the individual. The development of tests of fetal heart function such as antenatal cardiotocography have provided a means of assessing cardiac function and, to a certain extent, the functioning of parts of the autonomic nervous system. However such tests can only indirectly assess cortical function.

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“…Previous studies have examined the fetal cardiovascular responses during inspired OL using concentrations of %20% (Hellman et ul. 1961;John 1965;Copher & Huber 1967). The mild tachycardia observed in some of these studies may have been induced by maternal anxiety and catecholamine release.…”

Section: Discussionmentioning

confidence: 99%

The changes in fetal habituation patterns due to a decrease in inspired maternal oxygen

Leader

Baillie

1988

BJOG

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Habituation is widely regarded as a basic form of learning. A fully functioning central nervous system is probably required for a normal habituation pattern. Habituation of the behavioural response to vibroacoustic stimulation was studied in 23 normal human fetuses whose gestational age was 36 or more weeks. Eighteen were tested whilst their mothers brcathcd either air or a 12% oxygen in nitrogen mixture. The test was rcpeated the tollowing day with the order of the gases reversed. In addition five fetuses were tested while their mothers breathed air on both occasions. Of the 28 fetuses 17 had a normal habituation pattern when tested in air but only two had a normal pattern when their mothers breathed 12% 0,. Four of the five fetuses tested both days in air had normal patterns on the second day. Altering the amount of inspired maternal O2 alters the fetal habituation pattern.

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The Effect of Maternal Hypoxia on the Heart Rate of the Foetus in Utero

Cited by 7 publications

References 9 publications

Recent Advances in Pain Relief in Childbirth I: Inhalation and Systemic Analgesia

Recent Advances in Pain Relief in Childbirth I: Inhalation and Systemic Analgesia

Fetal Habituation

The changes in fetal habituation patterns due to a decrease in inspired maternal oxygen

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