The Effect of Maternal Estrogens On the Vaginal Epithelium of the Newborn

Parker, Charles E.; Johnson, Frances C.

doi:10.1177/000992286300200706

Cited by 2 publications

(1 citation statement)

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“…During the first few weeks of life, parts of female reproductive tract (FRT) like the vagina and vulva, are affected by residual maternal estrogens [11]. As the vagina mucosa contains a rich glycogen supply, it has been proposed that lactic acid bacteria like Lactobacillus species quickly colonize it within the first 24 h of birth [4,12].…”

Section: The Development Of the Vaginal Microbiome: How Does It Change Throughout A Woman's Life?mentioning

confidence: 99%

Finding a Balance in the Vaginal Microbiome: How Do We Treat and Prevent the Occurrence of Bacterial Vaginosis?

et al. 2021

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Bacterial vaginosis (BV) has been reported in one-third of women worldwide at different life stages, due to the complex balance in the ecology of the vaginal microbiota. It is a common cause of abnormal vaginal discharge and is associated with other health issues. Since the first description of anaerobic microbes associated with BV like Gardnerella vaginalis in the 1950s, researchers have stepped up the game by incorporating advanced molecular tools to monitor and evaluate the extent of dysbiosis within the vaginal microbiome, particularly on how specific microbial population changes compared to a healthy state. Moreover, treatment failure and BV recurrence rate remain high despite the standard antibiotic treatment. Consequently, researchers have been probing into alternative or adjunct treatments, including probiotics or even vaginal microbiota transplants, to ensure successful treatment outcomes and reduce the colonization by pathogenic microbes of the female reproductive tract. The current review summarizes the latest findings in probiotics use for BV and explores the potential of vaginal microbiota transplants in restoring vaginal health.

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Section: The Development Of the Vaginal Microbiome: How Does It Change Throughout A Woman's Life?mentioning

confidence: 99%