The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Homan, Tobias; Hiscox, Alexandra; Mweresa, Collins K.; Masiga, Daniel; Mukabana, Wolfgang R; Oria, Prisca A.; Maire, Nicolás; Pasquale, Aurelio Di; Silkey, Mariabeth; Alaii, Jane; Bousema, Teun; Leeuwis, C.; Smith, T.; Takken, Willem

doi:10.1016/s0140-6736(16)30445-7

Cited by 112 publications

(152 citation statements)

References 26 publications

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“…41 61-63 ▸ Odour-baited traps targeting host-seeking mosquitoes: Recent large-scale epidemiological trials have conclusively demonstrated mass suppression of the notoriously efficient African vector Anopheles funestus, and dramatically reduced malaria transmission by this widely distributed mosquito. 71 These solar-powered traps are entirely self-sufficient in terms of electrical power and also provide sufficient surplus to provide household lighting and charge mobile phones. Given these direct benefits at the household level, irrespective of the impact on mosquitoes or malaria transmission, it may therefore be possible to distribute such traps programmatically through horizontal delivery mechanisms.…”

Section: Recommendations For Policymentioning

confidence: 99%

Developing an expanded vector control toolbox for malaria elimination

et al. 2017

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Vector control using long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) accounts for most of the malaria burden reductions achieved recently in low and middle-income countries (LMICs). LLINs and IRS are highly effective, but are insufficient to eliminate malaria transmission in many settings because of operational constraints, growing resistance to available insecticides and mosquitoes that behaviourally avoid contact with these interventions. However, a number of substantive opportunities now exist for rapidly developing and implementing more diverse, effective and sustainable malaria vector control strategies for LMICs. For example, mosquito control in high-income countries is predominantly achieved with a combination of mosquito-proofed housing and environmental management, supplemented with large-scale insecticide applications to larval habitats and outdoor spaces that kill off vector populations en masse, but all these interventions remain underused in LMICs. Programmatic development and evaluation of decentralised, locally managed systems for delivering these proactive mosquito population abatement practices in LMICs could therefore enable broader scale-up. Furthermore, a diverse range of emerging or repurposed technologies are becoming available for targeting mosquitoes when they enter houses, feed outdoors, attack livestock, feed on sugar or aggregate into mating swarms. Global policy must now be realigned to mobilise the political and financial support necessary to exploit these opportunities over the decade ahead, so that national malaria control and elimination programmes can access a much broader, more effective set of vector control interventions.

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Section: Recommendations For Policymentioning

confidence: 99%

Developing an expanded vector control toolbox for malaria elimination

et al. 2017

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“…Here we undertook a study in western Kenya on the shores of Lake Victoria where LLIN ownership and usage is high and vector densities indoors have decreased as a consequence [31–33]. Shifts in the relative abundance of primary vector species have been described [34]; whilst the overall number of An.…”

Section: Introductionmentioning

confidence: 99%

Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western Kenya

et al. 2017

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BackgroundMalaria vector mosquitoes with exophilic and zoophilic tendencies, or with a high acceptance of alternative blood meal sources when preferred human blood-hosts are unavailable, may help maintain low but constant malaria transmission in areas where indoor vector control has been scaled up. This residual transmission might be addressed by targeting vectors outside the house. Here we investigated the potential of insecticide-treated cattle, as routinely used for control of tsetse and ticks in East Africa, for mosquito control.MethodsThe malaria vector population in the study area was investigated weekly for 8 months using two different trapping tools: light traps indoors and cattle-baited traps (CBTs) outdoors. The effect of the application of the insecticide deltamethrin and the acaricide amitraz on cattle on host-seeking Anopheles arabiensis was tested experimentally in field-cages and the impact of deltamethrin-treated cattle explored under field conditions on mosquito densities on household level.ResultsCBTs collected on average 2.8 (95% CI: 1.8–4.2) primary [Anopheles gambiae (s.s.), An. arabiensis and An. funestus (s.s.)] and 6.3 (95% CI: 3.6–11.3) secondary malaria vectors [An. ivulorum and An. coustani (s.l.)] per trap night and revealed a distinct, complementary seasonality. At the same time on average only 1.4 (95% CI: 0.8–2.3) primary and 1.1 (95% CI: 0.6–2.0) secondary malaria vectors were collected per trap night with light traps indoors. Amitraz had no effect on survival of host-seeking An. arabiensis under experimental conditions but deltamethrin increased mosquito mortality (OR 19, 95% CI: 7–50), but only for 1 week. In the field, vector mortality in association with deltamethrin treatment was detected only with CBTs and only immediately after the treatment (OR 0.25, 95% CI: 0.13–0.52).ConclusionsEntomological sampling with CBTs highlights that targeting cattle for mosquito control has potential since it would not only target naturally zoophilic malaria vectors but also opportunistic feeders that lack access to human hosts as is expected in residual malaria transmission settings. However, the deltamethrin formulation tested here although used widely to treat cattle for tsetse and tick control, is not suitable for the control of malaria vectors since it causes only moderate initial mortality and has little residual activity.

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“…Once again, 3‐MB was identified as one of the kairomones involved in attractiveness. Interestingly, 2‐MB and 3‐MB have also been included within the synthetic blends used in odour‐baited trap dedicated to malaria mosquitoes (Mweresa et al ., ; Homan et al ., ). Mukabana et al .…”

Section: Discussionmentioning

confidence: 98%

“…Once again, 3-MB was identified as one of the kairomones involved in attractiveness. Interestingly, 2-MB and 3-MB have also been included within the synthetic blends used in odour-baited trap dedicated to malaria mosquitoes (Mweresa et al, 2014;Homan et al, 2016). Mukabana et al (2012) showed that the increased concentration of 3-MB in the blend enhanced significantly mosquito attraction.…”

Section: Discussionmentioning

confidence: 99%

Identification of human skin bacteria attractive to the Asian Tiger mosquito

Michalet

Minard

Chevalier

et al. 2019

Environmental Microbiology

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Summary Aedes albopictus is a vector of arboviruses and filarial nematodes. Originating from Asia, this mosquito has rapidly expanded its geographical distribution and colonized areas across both temperate and tropical regions. Due to the increase in insecticide resistance, the use of environmentally friendly vector control methods is encouraged worldwide. Using methods based on semiochemicals in baited traps are promising for management of mosquito populations. Interestingly, human skin microbiota was shown to generate volatile compounds that attract the mosquito species Anopheles gambiae and Aedes aegypti. Here, we investigated the composition of skin bacteria from different volunteers and the attractive potential of individual isolates to nulliparous Ae. albopictus females. We showed that three out of 16 tested isolates were more attractive and two were more repulsive. We identified dodecenol as being preferentially produced by attractive isolates and 2‐methyl‐1‐butanol (and to a lesser extent 3‐methyl‐1‐butanol) as being overproduced by these isolates compared with the other ones. Those bacterial volatile organic compounds represent promising candidates but further studies are needed to evaluate their potential application for baited traps improvement.

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The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial

Cited by 112 publications

References 26 publications

Developing an expanded vector control toolbox for malaria elimination

Developing an expanded vector control toolbox for malaria elimination

Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western Kenya

Identification of human skin bacteria attractive to the Asian Tiger mosquito

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