The Effect of Intravenous Dexamethasone on the Nausea Accompanying Vestibular Neuritis: A Preliminary Study

Kim, Ji Chan; Woon, Wang; Chang, Dong Sik; Lee, Ho Yun

doi:10.1016/j.clinthera.2015.09.010

Cited by 11 publications

(48 citation statements)

References 23 publications

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“…Pure-tone average was calculated using the mean of hearing thresholds at 500 Hz, 1, 2, and 3 kHz. For cVEMP tests, the latencies and amplitudes of the p13 and n23 waves were recorded with Navigator Pro software (Bio-logic Systems Corp, Mundelein, IL, USA) [ 13 ]. cVEMP asymmetry ratio was calculated using the following formula: (amplitudes difference/sum of amplitude)×100.…”

Section: Methodsmentioning

confidence: 99%

Clinical Characteristics of Dizziness Associated with Acute Peripheral Facial Palsy

et al. 2018

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Background and ObjectivesWe aimed to assess the clinical significance of dizziness associated with acute peripheral facial palsy (APFP).Subjects and MethodsMedical records of patients who visited an otorhinolaryngology clinic at a university hospital and were admitted for treatment of APFP between 2014 and 2016 were thoroughly reviewed.ResultsIn total, 15.3% (n=15) of patients had dizziness. Continuous, rotatory dizziness without exacerbating factors was most common and frequently accompanied by nausea/vomiting. Dizziness disappeared within 1 week during the hospitalization period. Patients with Ramsay Hunt syndrome (31.0%) had dizziness more frequently than those with Bell’s palsy (8.7%). In addition, higher hearing thresholds and pain around the ear was reported more often in dizzy patients (p<0.05). Logistic regression analysis revealed that the initial House-Brackmann grade of facial paralysis was solely associated with final recovery, but dizziness was not associated with prognosis.ConclusionsPatients with APFP may have transient dizziness in the early stage, which may be more frequently accompanied by worse hearing thresholds and/or pain around the ear. However, these symptoms including dizziness seem to be unrelated to final prognosis.

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Section: Methodsmentioning

confidence: 99%

Clinical Characteristics of Dizziness Associated with Acute Peripheral Facial Palsy

et al. 2018

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“…As the studies [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] showed different outcome criteria, a re-coding was performed forming a composite endpoint. The following criteria were judged as good clinical outcome event in the acute phase (Outcome I):…”

Section: Evaluation Conceptmentioning

confidence: 99%

Corticosteroids in patients with vestibular neuritis: An updated meta‐analysis

Bogdanova

Dlugaiczyk

Heckmann

et al. 2022

Acta Neuro Scandinavica

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“…The duration of the corticosteroid intervention ranged from 1 to 21 days. The most common corticosteroids used were dexamethasone 21,22,26 and methylprednisolone. 13,23,25 Records idenƟfied through database searching (n = 1375) Treatment: (n = 51) dexamethasone 12 mg (IV), diazepam 10 mg in 500 mL of 0.9% saline (IV), and thiethylperazine 6.5 mg subcutaneously.…”

Section: Description Of Included Studiesmentioning

confidence: 99%

“…11,21,23,24 The vestibular exercise program across the 7 studies were variable. 11,21,[22][23][24][25]27 The details of the program are presented in Supplemental Tables S3 and S4 (available online).…”

Section: Screeningmentioning

confidence: 99%

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Systematic Review and Meta‐analysis: Effectiveness of Corticosteroids in Treating Adults With Acute Vestibular Neuritis

Leong

Lau

Stewart

et al. 2021

Otolaryngol.--head neck surg.

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Objectives To determine whether steroids are effective in treating adults with acute vestibular neuritis. Data Sources PubMed, Embase, CINAHL, Cochrane CENTRAL, Web of Science, CAB Abstract, ICTRP, LILACS, PEDRO, ClinicalTrials.Gov, Google Scholar, NARIC, and OT Seeker. Review Methods A systematic review was undertaken for articles reporting subjective and/or objective outcomes of corticosteroids in adults with acute vestibular neuritis between December 2010 and October 2019. Reports of patient recovery from clinical vestibular outcomes at various time points and adverse effects from corticosteroids were of interest. Statistical analysis included qualitative and quantitative assessments. A limited meta-analysis of the data was performed through a random effects model. Results Eight studies met the criteria, and 6 were included in the meta-analysis. No significant differences between the groups (corticosteroid vs placebo, corticosteroid vs vestibular exercise, or corticosteroid vs combination of vestibular exercise and corticosteroid) were reported in the proportion of patients with complete recovery at 1, 6, and 12 months. The corticosteroid group had significantly better caloric recover at 1 month (95% CI, –16.33 to –0.32); however, there was no significant difference to the overall effect between the groups across 12 months. Subjective recovery did not differ between the groups. Five of the 8 studies reported on adverse effects from corticosteroids. Conclusion There is insufficient evidence to support the use of corticosteroids in managing acute vestibular neuritis in adults. At present, corticosteroids appear to have short-term benefits in canal paresis but no long-term benefits in canal paresis and symptomatic recovery. Future studies should consider including a wider variety of clinical vestibular tests and frequent acute follow-ups to monitor the effects of corticosteroids.

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The Effect of Intravenous Dexamethasone on the Nausea Accompanying Vestibular Neuritis: A Preliminary Study

Cited by 11 publications

References 23 publications

Clinical Characteristics of Dizziness Associated with Acute Peripheral Facial Palsy

Clinical Characteristics of Dizziness Associated with Acute Peripheral Facial Palsy

Corticosteroids in patients with vestibular neuritis: An updated meta‐analysis

Systematic Review and Meta‐analysis: Effectiveness of Corticosteroids in Treating Adults With Acute Vestibular Neuritis

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