1965
DOI: 10.1016/s0015-0282(16)35650-3
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The Effect of Intrauterine Foreign Bodies on Pregnancy in the Rabbit

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1967
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Cited by 31 publications
(12 citation statements)
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“…Once implantation has occurred in an IUD uterus, then the gross presence of a foreign body could reasonably be expected to disturb the balance of function within the uterus and cause death of the embryo. Adams & Eckstein (1965a) have also suggested that the post-implantational embryonic death was the result of interference with placental function. The apparent action of an IUD in causing post-implantational embryonic death in the rabbit may not be relevant to the basic problems of IUD action in women and experimental animals.…”
Section: Discussionmentioning
confidence: 99%
“…Once implantation has occurred in an IUD uterus, then the gross presence of a foreign body could reasonably be expected to disturb the balance of function within the uterus and cause death of the embryo. Adams & Eckstein (1965a) have also suggested that the post-implantational embryonic death was the result of interference with placental function. The apparent action of an IUD in causing post-implantational embryonic death in the rabbit may not be relevant to the basic problems of IUD action in women and experimental animals.…”
Section: Discussionmentioning
confidence: 99%
“…Doyle & Margolis (1963) found that a suture in the uterine lumen of the rat prevented implantation of blastocysts. This was soon followed by similar studies on the rabbit (Adams & Eckstein, 1964), cow (Hawk, Conley, Brinsfield & Righter, 1965) and ewe (Hawk, 1965 …”
mentioning
confidence: 88%
“…Investigations on the mode of action of IUDs have revealed that these devices may be acting by different mechanisms in different species and, since the material from which these devices are made varies, this may also affect their mode of action. In general, it appears that an IUD prevents conception by disturbing the implanta¬ tion processes in some manner in women (Jessen, Lane & Greene, 1963), rats (Doyle & Margolis, 1963), rabbits (Adams & Eckstein, 1965) and cows (Hawk, Conley, Brinsfield & Righter, 1965). There is a lack of information on the biochemical changes produced by IUDs.…”
Section: Introductionmentioning
confidence: 99%