The Effect of Intrauterine Foreign Bodies on Pregnancy in the Rabbit

Adams, C. E.; Eckstein, Peter P.

doi:10.1016/s0015-0282(16)35650-3

Cited by 31 publications

(12 citation statements)

References 5 publications

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“…Once implantation has occurred in an IUD uterus, then the gross presence of a foreign body could reasonably be expected to disturb the balance of function within the uterus and cause death of the embryo. Adams & Eckstein (1965a) have also suggested that the post-implantational embryonic death was the result of interference with placental function. The apparent action of an IUD in causing post-implantational embryonic death in the rabbit may not be relevant to the basic problems of IUD action in women and experimental animals.…”

Section: Discussionmentioning

confidence: 99%

Contraceptive Action of Intra-Uterine Devices in the Rabbit

Marston¹,

Chang²

1969

Reproduction

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A simple suture intra-uterine device (IUD), occupying almost the entire length of the uterine horn, was used to study the effect of an IUD upon conception in the rabbit.After being mated, rabbits were killed at 84, 132, 156 and 180 hr and at 14 days. Additional animals were examined at 14 days after the IUD had been removed 84, 132 and 156 hr after mating.The IUD was not completely contraceptive, but it induced considerable pre-implantational embryonic death between 156 and 180 hr after mating.

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Section: Discussionmentioning

confidence: 99%

Contraceptive Action of Intra-Uterine Devices in the Rabbit

Marston¹,

Chang²

1969

Reproduction

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“…Doyle & Margolis (1963) found that a suture in the uterine lumen of the rat prevented implantation of blastocysts. This was soon followed by similar studies on the rabbit (Adams & Eckstein, 1964), cow (Hawk, Conley, Brinsfield & Righter, 1965) and ewe (Hawk, 1965 …”

mentioning

confidence: 88%

Intra-Uterine Foreign Body and Pregnancy in Pigs

Rathmacher¹,

Anderson²,

Kawata³

et al. 1967

Reproduction

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“…Investigations on the mode of action of IUDs have revealed that these devices may be acting by different mechanisms in different species and, since the material from which these devices are made varies, this may also affect their mode of action. In general, it appears that an IUD prevents conception by disturbing the implanta¬ tion processes in some manner in women (Jessen, Lane & Greene, 1963), rats (Doyle & Margolis, 1963), rabbits (Adams & Eckstein, 1965) and cows (Hawk, Conley, Brinsfield & Righter, 1965). There is a lack of information on the biochemical changes produced by IUDs.…”

Section: Introductionmentioning

confidence: 99%