Abstract:Using the Falck-Hillarp histofluorescence method we studied the effect of gamma-aminobutyric acid (GABA) or gamma-hydroxybutyric acid (GHBA) on catecholaminergic (CA) and serotoninergic (5-HT) neurons in the rat brain. Both GABA as well as GHBA enhanced the CA fluorescence in noradrenergic (NA) terminals in the cerebellar cortex, which suggested that the NA content increased in these terminals. GHBA but not GABA also enhanced the fluorescence in dopaminergic (DA) terminals in the neostriatum and limbic structu… Show more
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