The Effect of Intraoperative Body Temperature on Postoperative Nausea and Vomiting in Pediatric Patients

Risk factors and outcomes of intraoperative hypothermia in neonatal and infant patients undergoing general anesthesia and surgery

“…The study recorded perioperative data of consecutive infants (between 1 and 12 months old) from 1 October 2021 to 31 March 2022 and neonates from 1 April 2021 to 31 March 2022 who underwent noncardiac surgeries. Exclusion criteria included patients with (1) preoperative hypothermia (<36°C) or hyperthermia (>38°C); (2) core temperature >38.5°C due to infection or other reasons within three days before surgery; (3) a history of hypothyroidism or hyperthyroidism or other endocrine disorders which may influence body temperature; (4) thermoregulation abnormalities such as malignant hyperthermia or neuroleptic malignant syndrome; (5) therapeutic hypothermia; (6) preoperative drugs usage that might influence body temperature such as NSAIDs; and (7) no core temperature monitored or data lost.…”

“…Intraoperative hypothermia, generally defined as a decrease in core temperature below 36°C during surgeries, is one of the most common physiological disturbances during general anesthesia in pediatric patients ( 1 , 2 ). Hypothermia is closely related to postoperative cardiovascular events ( 3 ), coagulopathies ( 4 ), surgical-wound infection ( 5 ), nausea and vomiting ( 6 ), pain ( 7 ), increased blood loss, and prolonged recovery time ( 8 , 9 ). In neonates and infants, cold stress can induce multiple pathophysiological distress such as catecholaminergic response, vasoconstriction, increased metabolism, and decreased lung surfactant synthesis; all these may lead to pulmonary hypertension, tissue hypoxia, arterial hypotension, hypoperfusion metabolic acidosis, and hypoglycaemia ( 10 ).…”