The effect of internal limiting membrane peeling on chronic recalcitrant pseudophakic cystoid macular edema: a report of two cases

Vitrectomy with removal of the internal limiting membrane in chronic diabetic macular oedema

“…Peyman et al reported a positive effect of vitrectomy and removal of the ILM in two eyes with pseudophakic cystoid macular oedema [24]. In our study the functional results of 25 eyes with additional cystoid macular oedema are not statistically significant different from the results of 35 eyes presenting diffuse macular oedema only.…”

Vitrectomy with internal limiting membrane removal for clinically significant macular oedema

“…Oxygenation may also be improved by the removal of the usually thicker-than-normal ILM. Although the mechanism by which ILM removal is effective remains unknown, its benefits have been demonstrated in eyes undergoing surgery for pseudophakic CME [34], retinitis pigmentosa-related CME [7] and diffuse diabetic macular oedema [6], as well as in our study.…”

“…In a few reports, the effect of internal limiting membrane (ILM) removal has also been investigated [6,7,19,34]. We present here our preliminary study on 30 eyes with failed laser therapy.…”

“…Since the recognition of the potential role of vitreoretinal traction in the development of macular oedema [24], numerous studies on the efficacy of vitrectomy have been published [6,7,10,19,21,26,28,31,34,37,38,39,46,47]. In a few reports, the effect of internal limiting membrane (ILM) removal has also been investigated [6,7,19,34].…”

Macular Edema and Cataract Surgery

“…The iatrogenic induction of posterior vitreous detachment during standard pars plana vitrectomy (PPV) is believed to ameliorate the supply of oxygen to the affected retinal area and to relieve the macula from any possible traction that could contribute to the formation of the CME. A few studies have shown improvement after PPV alone (Pendergast et al, 1999), PPV combined with ILM peeling (Peyman et al, 2002) or PPV combined with IVT triamcinolone (Bencić et al, 2006). Likewise, in cases of vitreous incarceration in the anterior segment, anterior vitrectomy or YAG laser disruption of vitreous adhesions may have therapeutic effect.…”