The Effect Of İnitial Periodontal Therapy On Saliva And Plasma Total Antioxidant Capacity Of Non-Smoking Periodontitis Patients

Başer, Ülkü; Işık, Hikmet Gamsız; Ateş, Gökçen; Isik, Gulden

doi:10.5505/eudfd.2015.59672

Cited by 1 publication

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References 15 publications

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“…Studies that evaluated the total antioxidant capacity levels showed a decrease in antioxidants in non-smoking individuals with periodontal disease. The level of antioxidants rises again after the treatment (28,29). In another study, it was observed that the level of nitric oxide in saliva increased in patients with gingivitis, chronic and aggressive periodontitis as compared to healthy individuals, while adrenomedullin may be an important marker only in patients with aggressive periodontitis (8).…”

Section: Periodontal Diseases and Peri-implantitismentioning

confidence: 96%

Saliva as a Diagnostic Tool in Oral Diseases

Kart¹,

Yarat²

2020

Experimed

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Saliva is a body fluid, which is secreted from 3 major salivary glands (parotid, submandibular and sublingual) and many minor salivary glands. It contains organic and inorganic substances with 99% water, and has several functions such as contribution to articulation, digestion, cleansing and protection of the oral mucosa, and antimicrobial effects. The concentration of saliva's substances vary according to the responses to physiological processes in the human body. Containing genetic materials such as DNA and RNA also highlights saliva as a potential diagnostic tool. Saliva analysis has advantages such as being cheaper, non-invasive, easier patient cooperation, and low technical sensitivity compared to blood tests; it can be used in the diagnosis of many diseases or routine risk assessments. It is also promising for its advantages in collection and storage of the samples. Advances in molecular biology, genomics, and proteomics have revealed the importance of saliva in the detection of many diseases, coining the term salivaomics. The early diagnosis of the diseases in which symptoms can be seen in late stages, may provide an easier treatment and improve the prognosis. In this review, the biomarkers of saliva in the presence of different diseases and the advantages of their use in diagnosis were examined.

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Section: Periodontal Diseases and Peri-implantitismentioning

confidence: 96%