The effect of inhibitory nerve impulses on a crustacean muscle fibre

The specific ionic conductances and the ionic movements across the motoneuronal membrane that produce the inhibitory post‐synaptic potential

“…into a depolarizing i.p.s.p. This is similar to the alteration of inhibitory junctional potentials with change in membrane potential that occurs in the crustacean muscle, although in that case the reversal normally occurs at the resting potential (Fatt & Katz, 1953).…”

“…by altering ionic concentrations on one or other side of the post-synaptic membrane. For example the effect of varying the external potassium concentration has been studied in attempts to discover the ionic mechanisms producing the inhibitory potentials of crustacean muscle (Fatt & Katz, 1953) and mammalian heart (Burgen & Terroux, 1953). Analogous experiments on mammalian motoneurones in situ are technically difficult, and hitherto only a few preliminary attempts have been made.…”

L‐Glutamate activates excitatory and inhibitory channels in Drosophila larval muscle

“…The current carrier responsible for this hyperpolarizing response was not identified. Arthropod muscles possess both excitatory and inhibitory synapses [3,4] and, more recently, excitatory and inhibitory receptor channels activated by L-GIu have been described [5][6][7]. However, single-channel currents activated by L-Glu have not been recorded in Drosophila muscle.…”

Voltage‐current relationship of a carbachol‐induced potassium‐ion pathway in Aplysia neurones.

“…The general success of models for synaptic transmission based on the idea that the activated chemosensitive post-synaptic membrane may be represented by a constant resistance in series with a battery (Fatt & Katz, 1951, 1953 suggests that the ion pathways produced by the action of transmitter-like substances have voltage-current relationships which, to a first approximation at least, are linear. Detailed information however is lacking.…”