“…First, the accuracy of movement control decreases (Repin, 1981; Kreidich et al, 1982; Grigorieva and Kozlovskaya, 1985; Kirenskaya et al, 1985; Sosnina et al, 2016). It has also been shown that the cortical organization of voluntary movements is changed (Kirenskaya et al, 2006; Tomilovskaya et al, 2008), and that the systems of posture and locomotion control suffer greatly (Melnik et al, 2006; Shpakov et al, 2008; Sayenko et al, 2016; Amirova et al, 2017). Similarly, studies of resting state brain activity revealed the changes similar to those obtained in a real space flight, indicating that support withdrawal is the main contributor to brain activity alterations and decline in the function of corticospinal tract function in weightlessness (Kuznetsova et al, 2015; Lazarev et al, 2018).…”