The effect of Ibuprofen on female and male reproduction of the open thelyca marine shrimp,Litopenaeus

Abstract

A research was designed to explore the effect of ibuprofen (IBU) as an intervening agent for prostaglandin biosynthesis on male and female reproduction of three species of Litopenaeus. Ovarian maturation was studied in L. stylirostris and L. vannamei injected periodically with IBU at 0.01 and 0.1 μg g−1 body weight (b.w.) and treated for unilateral eyestalk ablation. IBU at 0.1 μg induced a statistically (P < 0.05) higher rate of L. vannamei females with developing ovaries (45 ± 19%) as compared with controls (12 ± 8%) during 5 weeks; L. stylirostris did not activate vitellogenesis under this experimental protocol. IBU was also evaluated for male sexuality in L. occidentalis, L. stylirostris and L. vannamei. Periodic injections of IBU had no effect on sperm counts and spermatophore weights; however, sperm abnormalities in IBU 0.1 μg treated L. occidentalis and L. stylirostris were very low. In L. stylirostris, the renovation of normal spermatophores was remarkably improved in IBU treated males as compared with controls, but in L. vannamei spermatophore deterioration was not affected. The findings of this research support the hypothesis that prostaglandins are involved in penaeid reproduction playing a negative physiological role; however, altered steroidogenic pathways could also be involved.

Effects of Ibuprofen and Caffeine Concentrations on the Common Bed Bug (Cimex lectulatius L.) Feeding and Fecundity

“…One reason for the reduction in egg produced may be that Ibuprofen affected the egg development in the bed bugs. AlfaroMontoya [21] has shown that Ibuprofen negatively affected marine shrimp ovaries. Tesh and Guzman [40] fed three mosquito species various concentrations of ivermectin in human blood and recorded mortality and effect on fertility.…”

“…There were studies on the impact of Ibuprofen on aquatic life, such as in Daphnia magna Mueller, Litopenaeus spp. Farfante and Planorbis carinatus Muller [19][20][21][22]. Heckmanna et al [19,20] revealed that the population growth rate in water fleas (Daphnia spp.)…”

“…was significantly reduced when exposed to Ibuprofen, and the survival was affected at the highest concentration. Alfaro-Montoya [21] studied the impact of Ibuprofen on marine shrimps (Litopenaeus spp.) and found significant differences in treated females with developing ovaries (45 ± 19%) as compared with females in control (12 ± 8%).…”

Avances biotecnológicos sobre maricultura en Costa Rica. Una revisión de la investigación desarrollada por la Escuela de Ciencias Biológicas de la Universidad Nacional

“…En los machos, el ibuprofeno no ejerció ningún efecto sobre el recuento espermático y el peso del espermatóforo, sin embargo, redujo el número de anomalías espermáticas en L. occidentalis y L. stylirostris y mejoró la renovación del espermatóforo en L. stylirostris. Los hallazgos de esta investigación apoyan la hipótesis de que las prostaglandinas están implicadas en la reproducción de peneidos (Alfaro-Montoya, 2015).…”

La experiencia del cultivo comercial de camarones marinos en estanques de producción en Costa Rica

“…Además, se logró descubrir la localización de la glándula androgénica en varias especies de camarones (Alfaro-Montoya & Hernández, 2012), lo que permitirá disponer de una base anatómica precisa para la manipulación y el estudio de esta importante glándula que controla la masculinidad en los crustáceos. También se está investigando el papel de las prostaglandinas, cuya función en el control de la reproducción de estos animales marinos no ha sido establecida (Alfaro-Montoya, 2013). Finalmente, se está desarrollando la tecnología de reversión sexual y producción de larvas 100% hembras, de mayor tasa de crecimiento, aplicando técnicas de manipulación sexual y biología molecular en L. vannamei.…”