The Effect of Hyperthermia on Aqueous Humor Dynamics in Rabbits

Krupin, Theodore; Bass, B.S. Jonathan; Oestrich, Charles; Podos, Steven M.; Becker, Bernard

doi:10.1016/0002-9394(77)90567-0

Cited by 8 publications

(3 citation statements)

References 5 publications

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“…The effects of physical exercise on IOP have received some attention since the be-ginning of the 20th century (2) and there have been reports suggesting that IOP decreases during exercise (2)(3)(4)(5)(6)(7)(8)(9). However, these studies often failed to control for variables such as the type, intensity and duration of exercise, or subject age and level of fitness and possible tonometric errors (10).…”

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confidence: 99%

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Effects of submaximal exercise with water ingestion on intraocular pressure in healthy human males

Moura

Rodrigues

Waisberg

et al. 2002

Braz J Med Biol Res

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The effects of exercise and water replacement on intraocular pressure (IOP) have not been well established. Furthermore, it is not known whether the temperature of the fluid ingested influences the IOP response. In the present study we determined the effect of water ingestion at three temperatures (10, 24 and 38ºC; 600 ml 15 min before and 240 ml 15, 30 and 45 min after the beginning of each experimental session) on the IOP of six healthy male volunteers (age = 24.0 ± 3.5 years, weight = 67.0 ± 4.8 kg, peak oxygen uptake (VO 2peak ) = 47.8 ± 9.1 ml kg -1 min -1 ). The subjects exercised until exhaustion on a cycle ergometer at a 60% VO 2peak in a thermoneutral environment. IOP was measured before and after exercise and during recovery (15, 30 and 45 min) using the applanation tonometry method. Skin and rectal temperatures, heart rate and oxygen uptake were measured continuously. IOP was similar for the right eye and the left eye and increased postwater ingestion under both exercising and resting conditions (P<0.05) but did not differ between resting and exercising situations, or between the three water temperatures. Time to exhaustion was not affected by the different water temperatures. Rectal temperature, hydration status, heart rate, oxygen uptake, carbon dioxide extraction and lactate concentration were increased by exercise but were not affected by water temperature. We conclude that IOP was not affected by exercise and that water ingestion increased IOP as expected, regardless of water temperature.

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confidence: 99%

“…Most papers reviewed report a decrease in IOP after different types of exercises (2)(3)(4)(5)(6)(7)(8)(9)(12)(13)(14)(15)(16)(17)(18). Some studies showed increases of IOP after exercise (1,19), while others found either no effect on IOP or variable results (20).…”

mentioning

confidence: 99%

Effects of submaximal exercise with water ingestion on intraocular pressure in healthy human males

Moura

Rodrigues

Waisberg

et al. 2002

Braz J Med Biol Res

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“…After then, it begins to drop and returns to pre-intubation levels anywhere between 5 and 10 minutes. We hypothesised that administering 0.6 micrograms per kilogramme of body weight of dexmedetomidine intravenously 15 minutes prior to the administration of succinyl choline and intubation would reduce these stress reactions, and we set out to test this hypothesis in the current investigation [13][14][15] . Drugs like alpha-2 adrenergic agonists dexmedetomidine and clonidine have been studied in the past for their impact on blood pressure.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness and safety of dexmedetomidine in patients undergoing general anaesthesia: A randomized, single-blind trial

Ravirala¹,

Sohail²

2021

Int. J. Adv. Res. Med.

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Background: During the administration of general anaesthesia, laryngoscopy and endotracheal intubation must be performed. Just before intubation, succinyl choline is given. Intraocular pressure, heart rate, and blood pressure may all rise as a result of this. Many medications have been tried and utilised to mitigate this stress reaction. Dexmedetomidine is a sedative, anxiolytic, and analgesic since it is an alpha2 adrenergic agonist. Methods: For this study, researchers utilised a randomised, single-blind, placebo-controlled design.

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Augeninnendruck und Tonometrie

Shields

1993

Glaukom

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The Effect of Hyperthermia on Aqueous Humor Dynamics in Rabbits

Cited by 8 publications

References 5 publications

Effects of submaximal exercise with water ingestion on intraocular pressure in healthy human males

Effects of submaximal exercise with water ingestion on intraocular pressure in healthy human males

Effectiveness and safety of dexmedetomidine in patients undergoing general anaesthesia: A randomized, single-blind trial

Augeninnendruck und Tonometrie

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