The effect of human recombinant epidermal growth factor on neovascularization and pedicle division time in a rat interpolation flap model
Aziz PARSPANCI,
Yavuz KEÇECİ,
Peyker TEMİZ
Abstract:Background/aim
In practice, waiting 2–3 weeks for interpolation flaps pedicle division result in certain morbidities and discomfort for patient. The division time of flap pedicle depends on neovascularization from the recipient bed and includes wound healing stages. We aimed to investigate the effect of recombinant human epidermal growth factor (rhEGF) on the flap viability during early pedicle division.
Materials and methods
Thirty-six rats were allocated to two main g… Show more
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