The Effect Of Honey Give As Oral Drops In Precipitating Epithelialization Of Lateral Palatal Defects Post TwoFlap Palatoplasty

Abstract

Background : Two-flap palatoplasty, which is a very common technique used including in our institution, will result in lateral palatal defects without any periosteal coverage. Faster epithelialization is expected to decrease wound contraction thus reducing scar formation, and in the long run will result in good maxillary growth. In our institution, the retrospective study showed a fair maxillary growth (mean GOSLON score=3.5). Thus, we explore possibilities to precipitate the epithelialization process in pursuit of good maxillary growth in the future.Method :This is a prospective cohort study conducted in Cipto Mangunkusumo Hospital, on consecutive patients who underwent two-flap palatopasty from October 2010-February 2011. We followed up these patients weekly for 4 consecutive weeks to observe the rate of epithelialization of the lateral palatal defects.Result : Two-flap palatoplasty was performed in 48 patients, 23 among them were given honey as oral drops. Eighty-seven point five percent had unilateral complete cleft lip and palate and 12.5% had bilateral complete cleft lip and palate. Faster epithelialization of the lateral palatal defects post two-flap palatoplasty was significantly in!uenced by intraoral honey application on the wound as oral drops (RR 2.1, 95% CI 1.314 - 3.391, p < 0.001).Conclusion: Honey given as oral drops significantly precipitates the epithelialization process of the lateral palatal defects post two flap palatoplasty 2.1 times faster.

Maxillary Growth Evaluation Of Patients With Unilateral Complete Cleft Lip And Palate After Two Flap Palatoplasty With Honey Oral Drops

“…This study was conducted in Cipto Mangunkusumo Hospital during June-October 2016. 1 All of the subjects in the previous study who met the inclusion criteria were included. The number of the control group were matched to the total subjects obtained from previous study.…”

“…The median age of the subjects were 26 months old (87,5% of subjects with UCCLP, while the 12,5% with BCCLP). 1 However, a long term data of these subjects is yet to be obtained. To evaluate whether the rapid epithelialization would affect the maxillary growth of the subjects, a long-term follow up data is required.…”

M3-4 and D1 for Palate Re-repair & Pharyngeal Flap

“…This patient needs closure of the fistula in two layers; nasal layer closure by turn in flaps and oral layer cover with well vascularized mucoperiosteal flap. Various options available may be buccinator flap (Bozola 1989;Licameli 1998;Dupoirieux 1999), nasal artery musculomucosal cutaneous flap (Percy 2012), FAMM flap (Pribaz 1992), or a tongue flap (Elsherbiny et al 2012).…”

“…Patient is advised honey intake 3-4 times daily with a plastic spoon, with no water intake afterward for 15 min. Honey promotes healing by multifaceted actions; moist environment, angiogenesis, and providing nutrition to the wound (Kreshanti et al 2012;Dewi and Gentur 2012).…”

“…She is advised honey one tablespoon 3-4 times daily with no water intake for 15 min afterwards. Honey promotes healing (Mukarramah and Sudjatmiko 2012;Kreshanti et al 2012).…”